Venue & Game Details
- First Pitch: 9:40 p.m. ET / 6:40 p.m. PT
- Venue: T-Mobile Park, Seattle, Washington
- Series: Game 1 of a 3-game interleague set
Weather Forecast (Seattle, WA)
- Conditions: Partly cloudy
- Temperature at First Pitch: ~70°F (21°C)
- Wind: 5–10 mph from the northwest
- Impact: Comfortable playing conditions; minimal wind effect.
Injury Report
St. Louis Cardinals
- Alec Burleson — 10-Day IL (wrist)
- John King — 15-Day IL (back)
- Brendan Donovan — 10-Day IL (groin)
- Nolan Arenado — 10-Day IL (shoulder)
- Zack Thompson — 60-Day IL (lat)
Seattle Mariners
- Jackson Kowar — 15-Day IL (shoulder)
- Trent Thornton — 60-Day IL (Achilles)
- Logan Evans — 15-Day IL (elbow)
- Gregory Santos — 60-Day IL (knee)
- Ryan Bliss — 60-Day IL (biceps)
Probable Pitchers
- Cardinals: Miles Mikolas (RHP) — 7–10, 4.89 ERA, 1.33 WHIP, 86 K
- Mariners: Bryan Woo (RHP) — 12–7, 3.02 ERA, 0.97 WHIP, 169 K
Team Records & Recent Form
- Cardinals: 31–38 on the road; 27–10 when hitting 2+ HR in a game.
- Mariners: 41–27 at home; .319 OBP (5th in AL).
Series History
- 2025 Season Series: First meeting of the year.
- Last Meeting: Mariners won 2 of 3 in 2023.
Betting Trends
- Mariners are 41–27 at home this season.
- Cardinals are 27–10 when hitting multiple home runs.
- Over has hit in 4 of Mariners’ last 10 games; Cardinals 3–7 to the over in that span.
Game Odds
St. Louis Cardinals 7.5
Seattle Mariners – 220
Odds Courtesy of Sports Odds Direct as of Sunday, September 7, 2025
