MLB Game Preview: San Francisco Giants (24-16) vs. Minnesota Twins (20-20)

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The San Francisco Giants and Minnesota Twins are set to face off in the final game of their three-game series at Target Field in Minneapolis. The Twins have been dominant at home, winning six straight games, while the Giants are looking to bounce back after a 3-1 loss in Game 1. First pitch is scheduled for May 11, 2025, at 2:10 PM ET.

Team Overview & Recent Form

San Francisco Giants (24-16, 2nd in NL West)

  • Last Five Games: Loss, Loss, Win, Win, Loss
  • Road Record: 10-9
  • Batting Average: .217 on the road
  • Key Players:
  • Logan Webb – 4.18 ERA on the road vs. 0.44 ERA at home, struggles away from Oracle Park.
  • Matt Chapman – Leads the team with eight home runs, providing power in the lineup.
  • Jung Hoo Lee – Batting .293, a key contact hitter for the Giants.

Minnesota Twins (20-20, 3rd in AL Central)

  • Last Five Games: Win, Win, Win, Win, Win
  • Home Record: 11-5
  • Batting Average: .254 at home
  • Key Players:
  • Joe Ryan – 0.88 WHIP at home, dominant in Target Field starts.
  • Byron Buxton – Nine home runs, batting .279, leading the Twins’ offense.
  • Trevor Larnach – Five home runs, providing clutch hitting in recent games.

Pitching Matchup

  • Giants: Logan Webb (RHP, 3-2, 3.45 ERA) – Has struggled on the road, allowing five earned runs in his last away start.
  • Twins: Joe Ryan (RHP, 4-2, 2.89 ERA) – Has been dominant at home, striking out 25 batters in 17 innings at Target Field.

Game Analysis & Predictions

  • Giants’ Strategy: San Francisco needs Webb to overcome his road struggles and their offense to step up against Ryan.
  • Twins’ Strategy: Minnesota has been red-hot at home, and their pitching has kept opponents in check.

Game Odds

San Francisco Giants      8.5

Minnesota Twins             – 150

Odds Courtesy of Sports Odds Direct as of Saturday, May 10, 2025