MLB Game Preview: San Diego Padres (62-50) vs. Arizona Diamondbacks (53-59)

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Arizona Diamondbacks logo

The San Diego Padres travel to Chase Field to face the Arizona Diamondbacks, opening a pivotal three-game NL West series. With San Diego surging toward a Wild Card spot and Arizona fighting to stay in the race, this Padres vs Diamondbacks MLB matchup is loaded with playoff implications, betting intrigue, and star power.

Game Overview

CategorySan Diego PadresArizona Diamondbacks
Record62–50 (2nd in NL West)53–59 (4th in NL West)
Road/Home Split26–31 (Road)26–28 (Home)
Season SeriesDiamondbacks lead 4–3
Betting OddsPadres -141Diamondbacks +119
Over/Under9.5 runs

San Diego enters the game as road favorites, having won 7 of their last 10, while Arizona has dropped 7 of 10 and is looking to reverse course at home.

Pitching Matchup

  • Padres Starter: JP Sears
    • Record: 7–9
    • ERA: 4.95
    • WHIP: 1.27
    • Strikeouts: 97
    • Strength: Solid control, but vulnerable to power bats
  • Diamondbacks Starter: Brandon Pfaadt
  • Record: 10–7
  • ERA: 5.03
  • WHIP: 1.30
  • Strikeouts: 98
  • Strength: Durable innings-eater, but inconsistent command

Both starters have mid-tier ERAs and will need run support to secure a win. Expect early offense if either pitcher struggles with location.

Key Players to Watch

Arizona Diamondbacks

  • Ketel Marte: .288 AVG, 21 HR, 44 RBI – Team leader in batting average and slugging
  • Corbin Carroll: 22 HR – Ranks 20th in MLB for home runs
  • Alek Thomas: 11-for-31 with 2 HR in last 10 games – Hot bat entering the series

San Diego Padres

  • Manny Machado: .299 AVG, 20 HR, 72 RBI – Top 10 in MLB batting average
  • Luis Arraez: .298 AVG, 21 doubles, 4 triples – Batting .415 over last 10 games
  • Fernando Tatis Jr.: .264 AVG, 17 HR, 63 walks – Elite OBP and power combo

Recent Form & Trends

TeamLast 10 GamesBatting AvgERARun Differential
Padres7–3.3033.38+20
D-backs3–7.2094.50–24

San Diego’s offense is clicking, while Arizona has struggled to generate runs and limit damage on the mound.

San Diego has won 60% of games when favored by -141 or more, while Arizona has just a 42.9% win rate as underdogs.

How to Watch

  • TV Broadcast: MLB Network, Bally Sports San Diego, Bally Sports Arizona
  • Streaming: MLB.TV, Fubo, FOX Sports App

Final Thoughts

This Padres vs Diamondbacks MLB game is a critical test for both teams. With Manny Machado and Luis Arraez leading a red-hot Padres lineup, and Brandon Pfaadt trying to stabilize Arizona’s rotation, expect a high-scoring affair. San Diego’s recent form and bullpen depth give them the edge, but Arizona’s home-field advantage and power bats could keep it close.

Game Odds

San Diego Padres             – 137

Arizona Diamondbacks 9.5

Odds Courtesy of Sports Odd Direct as of Sunday, August 3, 2025