First Pitch is scheduled for 1:10 PM ET (FOX Sports lists the matchup at 1:10 PM; ESPN lists 4:10 PM ET)
Weather Outlook (Inference)
No direct weather data was provided in the sources.
Early April in Boston typically features:
Low–mid 50s°F
Light breeze
Potential overcast or light drizzle
Fenway Park’s dimensions and cool spring air generally favor pitchers early in the season.
(Inference only — not sourced.)
Injury Report
Boston Red Sox
Johan Oviedo — 15‑Day IL (elbow)
Patrick Sandoval — 15‑Day IL (elbow)
Kutter Crawford — 15‑Day IL (wrist)
Anthony Seigler — 10‑Day IL (knee)
Triston Casas — 10‑Day IL (knee)
Romy Gonzalez — 60‑Day IL (shoulder)
Tanner Houck — 60‑Day IL (elbow)
San Diego Padres
Bryan Hoeing — 15‑Day IL (elbow)
Jason Adam — 15‑Day IL (quadriceps)
Yuki Matsui — 15‑Day IL (groin)
Matt Waldron — 15‑Day IL (lower body)
Joe Musgrove — 15‑Day IL (elbow)
Griffin Canning — 15‑Day IL (achilles)
Will Wagner — 10‑Day IL (oblique)
Sung‑Mun Song — 10‑Day IL (oblique)
Jhony Brito — 60‑Day IL (elbow)
Probable Pitching Matchup
San Diego — RHP Randy Vásquez
1–0, 0.00 ERA, 0.83 WHIP, 8 K
Coming off a dominant season debut.
Boston — LHP Connelly Early
0–0, 1.69 ERA, 1.31 WHIP, 6 K
Strong first outing; Boston expects him to stabilize the rotation.
Team Statistical Profile
San Diego Padres (2–5)
Team AVG: .202
Runs per game: 3.2
OBP: .280
Slugging: .301
Strikeouts: 51
Walks: 21
Team ERA: 4.00
WHIP: 1.30
FIP: 3.36
Boston Red Sox (2–5)
Snapped a five‑game losing streak with a 5–2 win in the series opener.
Limited Padres to four hits in Game 1.
Strong bullpen performance (Justin Slaten, Aroldis Chapman).
Recent Team Form
Padres — Last 5 Games
Loss vs BOS (5–2)
Win vs MIL
Loss vs MIL
Loss vs MIL
Win vs CIN
Red Sox — Last 5 Games
Win vs SD (5–2)
Loss vs CIN
Loss vs CIN
Loss vs CIN
Loss vs CIN
Key Player Matchups
Fernando Tatis Jr. (SD) vs. Connelly Early (BOS)
Tatis anchors the Padres lineup and is expected to rebound after a quiet opener.
Masataka Yoshida (BOS) vs. Randy Vásquez (SD)
Yoshida’s contact skills match up intriguingly with Vásquez’s movement-heavy arsenal.
Trevor Story (BOS)
Provides power and veteran presence in the heart of the order.
Manny Machado (SD)
Key run producer; Padres need him to spark the offense after being held to four hits in Game 1.
Series History
Boston leads the current series 1–0 after a 5–2 win on April 3.
Padres tied the opener 2–2 in the 5th before Boston’s three‑run response sealed the game.
Game Odds
San Diego Padres 7.5
Boston Red Sox – 149
Odds Courtesy of Sports Odds Direct as of Friday, April 3, 2026
