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MLB Game Preview: San Diego Padres (16-7) vs. Detroit Tigers (14-9)

The San Diego Padres (16-7) and Detroit Tigers (14-9) are set to face off in the second game of their three-game series on Tuesday, April 22, 2025, at Comerica Park in Detroit. The Tigers secured a 6-4 victory in the series opener, marking their fourth win in five games.

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Game Details

  • Date: Tuesday, April 22, 2025
  • Time: 6:40 PM ET
  • Venue: Comerica Park, Detroit, MI
  • TV Broadcast: Bally Sports San Diego, Bally Sports Detroit
  • Series Status: Tigers lead 1-0

Team Overview & Key Players

Detroit Tigers (14-9, 2nd in AL Central)

The Tigers have been strong at home, boasting an 8-2 record at Comerica Park. Their offense has been consistent, ranking ninth in the AL with a .387 slugging percentage.

Key Players

  • Spencer Torkelson (1B) – Leads the Tigers with seven home runs and 21 RBIs, hitting .288.
  • Zach McKinstry (INF) – Went 3-for-4 in Game 1, continuing his hot streak.
  • Kerry Carpenter (OF) – Batting .417 over his last 10 games.
  • Keider Montero (SP) – Set to start; holds a 0-1 record with a 9.00 ERA, looking to bounce back.

San Diego Padres (16-7, 1st in NL West)

The Padres have been dominant offensively, leading MLB with a .346 team on-base percentage. However, they struggled in Game 1, managing just seven hits.

Key Players

  • Fernando Tatis Jr. (OF) – Second on the team with eight home runs, looking to spark the offense.
  • Luis Arraez (INF) – Batting .256, but dealing with a neck injury.
  • Manny Machado (3B) – Provides veteran leadership, hitting .326 over his last 10 games.
  • Randy Vasquez (SP) – Set to start; holds a 1-1 record with a 1.74 ERA, aiming to keep Detroit’s bats in check.

Game 2 Pitching Matchup

PitcherTeamRecordERALast Start
Keider MonteroTigers0-19.005.0 IP, 5 ER vs. Royals
Randy VasquezPadres1-11.745.0 IP, 1 ER vs. White Sox

Montero struggled in his season debut, while Vasquez has been solid, allowing just four earned runs in four starts.

Game Outlook & Predictions

  • Tigers’ Strategy: Expect Detroit to rely on early offense, using Torkelson and McKinstry to set the tone.
  • Padres’ Adjustments: San Diego must capitalize on scoring opportunities and limit strikeouts against Montero.
  • X-Factor: Fernando Tatis Jr.’s ability to drive in runs could be the difference-maker.

Game Odds

San Diego Padres                             7.5

Detroit Tigers                                    – 115

Odds Courtesy of Sports Odds Direct as of Monday, April 21, 2025

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