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MLB Game Preview: Pittsburgh Pirates (32-49) vs. Milwaukee Brewers (44-36)

Game Details

  • Matchup: Pittsburgh Pirates (32–49) vs. Milwaukee Brewers (44–36)
  • Date: Wednesday, June 25, 2025
  • First Pitch: 2:10 PM ET
  • Venue: American Family Field, Milwaukee, WI
  • Broadcast: MLB Network (out-of-market), Bally Sports Wisconsin, AT&T SportsNet Pittsburgh, MLB.TV

Game Context & Series Outlook

This is the rubber match of a three-game series between the Brewers, who are surging in the NL Central, and the Pirates, who are looking to build momentum behind their ace. The series is tied 1–1 after Pittsburgh took the opener 5–4 and Milwaukee responded with a 9–3 win on Tuesday.

Wednesday’s finale features a marquee pitching duel between two of MLB’s most exciting young arms: Paul Skenes and Jacob Misiorowski.

Probable Pitchers

Pittsburgh Pirates: Paul Skenes (4–6, 1.85 ERA)

  • Leads MLB in ERA among qualified starters
  • 106 strikeouts in 102 IP
  • Has allowed 3 or fewer earned runs in 15 of 16 starts
  • Fastball averages 98.0 mph; elite whiff and chase rates

Milwaukee Brewers: Jacob Misiorowski (2–0, 1.64 ERA)

  • Rookie sensation with 11 IP, 1 H, 2 ER, 11 K
  • Threw 6 perfect innings in last start vs. Twins
  • Triple-digit fastball and elite spin rate
  • Making just his 3rd MLB start

Players to Watch

Pittsburgh Pirates

  • Nick Gonzales: .875 OPS; 17-for-43 with 2 HR in last 10 games
  • Andrew McCutchen: .259 AVG, 8 HR, 28 RBI; veteran leadership
  • Oneil Cruz: 13 HR, .404 SLG; day-to-day after benching for lack of hustle

Milwaukee Brewers

  • Christian Yelich: .264 AVG, 15 HR, 56 RBI; 8-game hitting streak
  • William Contreras: .273 AVG, 21 hits in last 21 games
  • Sal Frelick: Team-high .295 AVG; 9 doubles, 4 HR

Team Stats & Trends

CategoryPiratesBrewers
Record32–4944–36
Road/Home Record12–28 (away)24–16 (home)
Runs/Game (Last 10)3.35.1
Team ERA (Last 10)4.754.25
Batting Average (L10).243.317
Head-to-Head (2025)3–33–3

Milwaukee is 17–1 when hitting 2+ home runs in a game. Pittsburgh is 15–3 when scoring 5+ runs.

Expect a low-scoring pitcher’s duel between Skenes and Misiorowski. The Brewers’ deeper lineup and home-field edge give them a slight advantage, but this one could come down to the bullpens.

How to Watch Pirates vs Brewers – June 25, 2025

  • TV Channels: MLB Network (out-of-market), Bally Sports Wisconsin, AT&T SportsNet Pittsburgh
  • Streaming: MLB.TV, FuboTV (free trial available)
  • Radio: Brewers Radio Network (AM-620 WTMJ), Pirates Radio Network (KDKA-FM 93.7)

Game Odds

Pittsburgh Pirates            7

Milwaukee Brewers       – 111

Odds Courtesy of Sports Odds Direct as of Tuesday, June 24, 2025

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