MLB Game Preview: New York Yankees (66-57) vs. St. Louis Cardinals (61-63)

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St. Louis Cardinals logo

Busch Stadium, St. Louis, MO
First Pitch: 2:15 PM ET
Broadcast: ESPN, Bally Sports Midwest

Team Records & Form

TeamRecordLast 10 GamesRoad/Home SplitSeason Series
Yankees66–576–4 (.227 AVG)29–32 on roadLead 2–1
Cardinals61–634–6 (.263 AVG)35–29 at homeTrail 1–2

New York enters Sunday’s finale riding momentum from a 12–8 win on Saturday, powered by Trent Grisham’s four-hit performance. St. Louis looks to salvage the series behind veteran Miles Mikolas.

Pitching Matchup

PitcherTeamW–LERAWHIPK/BBNotes
Will WarrenYankees7–54.341.36140/49High K rate (26.3%); struggles with walks
Miles MikolasCardinals6–94.971.2879/22Reliable innings-eater; 3.21 ERA at home

Warren brings swing-and-miss stuff but can be erratic late in games. Mikolas has been steady at Busch Stadium and will need to keep the ball in the park against New York’s power bats.

Key Hitters to Watch

New York Yankees

  • Aaron Judge: .333 AVG, 39 HR, 88 RBI – 4th in MLB HR, 7th in RBI
  • Giancarlo Stanton: 12-for-28, 3 HR, 8 RBI in last 10 games
  • Ben Rice: 13-for-29, 3 HR, 9 RBI in last 10 games – breakout series

St. Louis Cardinals

  • Pedro Pagés: 13-for-29, 3 HR, 9 RBI in last 10 games – red hot
  • Alec Burleson: .284 AVG, 19 doubles, 15 HR – team leader in BA
  • Masyn Winn: .264 AVG, 25 doubles, 8 HR – dynamic top-of-order bat

Game Trends & Betting Insights

  • Yankees: 42–15 when scoring 5+ runs; 3.60 team ERA over last 10
  • Cardinals: 33–14 when allowing 0 HR; 5.16 team ERA over last 10
  • Over/Under: OVER has hit in 4 of last 5 Yankees games
  • Prediction: Yankees 6, Cardinals 4 (Over 9.5 runs)

Injury Report

New York Yankees

  • Gerrit Cole (elbow), Clarke Schmidt (forearm), Jonathan Loaisiga (back) – 60-Day IL
  • Amed Rosario (joint), Austin Slater (hamstring), Ryan Yarbrough (oblique) – 15-Day IL

St. Louis Cardinals

  • Nolan Arenado (shoulder), Zack Thompson (lat), John King (oblique) – IL
  • Willson Contreras, Brendan Donovan, Victor Scott II – day-to-day

GAME ODDS

New York Yankees           – 156

St. Louis Cardinals           9

Odds Courtesy of Sports Odds Direct as of Saturday, August 16, 2025