MLB Game Preview: Houston Astros (72-58) vs. Baltimore Orioles (59-70)

Game Info

• Venue: Oriole Park at Camden Yards, Baltimore, MD

Probable Pitching Matchup

Trevor Rogers will toe the rubber for Baltimore, carrying a 1.41 ERA, 0.79 WHIP and 67 strikeouts in 76.1 innings, while Houston counters with Spencer Arrighetti, who owns a 6.94 ERA, 1.63 WHIP and 21 strikeouts through his early-season work.

Team Records & Recent Trends

The Astros arrive at Camden Yards sporting a 72-58 record (34-31 on the road) and have split their last ten games, while the Orioles sit at 59-70 overall (30-33 at home) and have dropped three straight decisions.

Team	Overall	Home/Road	Last 5	Last 10
Astros	72-58	34-31 R	W-W-W-L-L	5-5, .195 BA, 5.43 ERA, –22 runs
Orioles	59-70	30-33 H	L-L-L-W-W	6-4, .261 BA, 3.63 ERA, +16 runs

Season Series

Houston holds a 4–2 edge over Baltimore in their 2025 meetings, looking to complete the sweep and solidify control of the head-to-head season slate.

Key Player Matchups

• Jackson Holliday (BAL): .246 AVG, 17 2B, 2 3B, 15 HR, 49 RBI
• Jeremiah Jackson (BAL): 14-for-35 with a double, triple and home run in his last 10 games
• Jeremy Pena (HOU): .304 AVG, 14 HR, 49 RBI
• Yainer Diaz (HOU): .308 AVG, 2 HR, 5 RBI in his past 10 contests

Injury Report

Baltimore’s injured list is extensive, headlined by Gary Sanchez (knee), Adley Rutschman (oblique), Jordan Westburg (ankle), Jorge Mateo (elbow), Tyler O’Neill (wrist), Tyler Wells (elbow) and Grayson Rodriguez (elbow) among others currently sidelined.

Houston’s injury report features LHP Josh Hader (left shoulder strain, 15-day IL), RHP Hayden Wesneski (right elbow inflammation, 60-day IL), OF Jake Meyers (right calf strain, 10-day IL), INF Brendan Rodgers (left oblique strain, 60-day IL) and OF Yordan Alvarez (right hand inflammation, 60-day IL).

How to Watch

• TV: MASN (BAL), AT&T SportsNet Southwest (HOU)
• Live Stream: MLB.tv (subject to local blackout restrictions)

With Rogers dominating on the mound and Houston’s powerful lineup looking to exploit Camden Yards, expect a classic pitcher-versus-power duel. Keep an eye on live in-game prop bets around first-five-innings runs allowed and long-ball props for Holliday and Pena. Weather conditions (mid-80s and partly cloudy) should offer ideal hitting—but don’t sleep on Rogers’ steady mix.