MLB Game Preview: Houston Astros (44-33) vs. Los Angeles Angels (37-39)

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Game Details

  • Matchup: Houston Astros vs. Los Angeles Angels
  • Date: Sunday, June 22, 2025
  • Time: 4:07 PM ET
  • Venue: Angel Stadium, Anaheim, CA
  • Broadcast: ESPN, Space City Home Network, MLB.TV

Series Recap & Stakes

This is the sixth meeting of the season between these AL West rivals. The Astros lead the season series 3-2 and are looking to clinch the set after a dramatic extra-innings win on Friday and a narrow loss on Saturday. Tensions have been high—Friday’s game even saw benches clear after a hit-by-pitch incident.

Houston Astros – Team Snapshot

  • Record: 44-33 (1st in AL West)
  • Road Record: 17-20
  • Last 10 Games: 7-3
  • Key Players:
  • Jeremy Peña: .324 AVG, 10 HR – team’s top hitter
  • Isaac Paredes: 16 HR, 45 RBI – power bat in the middle
  • Jake Meyers: 14-for-37 in last 10 games – red-hot form

Starting Pitcher:
Brandon Walter (0-0, 1.53 ERA) – The rookie lefty has impressed in three starts, allowing just 3 earned runs over 17.2 innings with 19 strikeouts.

Los Angeles Angels – Team Snapshot

  • Record: 37-39 (3rd in AL West)
  • Home Record: 16-17
  • Last 10 Games: 5-5
  • Key Players:
  • Taylor Ward: 19 HR, 52 RBI – team leader in power
  • Mike Trout: 11-for-35 in last 10 games – steady veteran presence
  • Zach Neto: 10 HR – fiery shortstop with a chip on his shoulder

Starting Pitcher:
José Soriano (4-5, 3.54 ERA) – The righty has been sharp lately, allowing just 1 run over his last 14 innings. He owns a 2.45 ERA in four career appearances vs. Houston.

Key Matchup Insights

  • Pitching Duel: Walter’s small-sample dominance vs. Soriano’s recent form makes this a compelling matchup.
  • Offensive Trends: Astros are hitting .272 over their last 10 games; Angels are at .220.
  • Injury Watch: Astros are missing Yordan Alvarez, Chas McCormick, and several pitchers; Angels are without Jorge Soler, Anthony Rendon, and Yoan Moncada.
  • X-Factor: Emotions are running high after Friday’s near-brawl—expect intensity from the first pitch.

Game Odds

Houston Astros                 – 113

Los Angeles Angels         9

Odds Courtesy of Sports Odds Direct as of Saturday, June 21, 2025