MLB Game Preview: Cleveland Guardians (64-61) vs. Arizona Diamondbacks (61-66)

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Arizona Diamondbacks logo

Game Details

  • Time: 3:40 PM ET
  • Venue: Chase Field, Phoenix
  • Series Status: Tied 1–1
  • Broadcast: ESPN, Bally Sports Great Lakes, Arizona Sports

Pitching Matchup

  • Guardians: Parker Messick (MLB debut)
  • Diamondbacks: Brandon Pfaadt (12–8, 5.01 ERA)

Messick gets the call-up after posting a 3.47 ERA in Triple-A, while Pfaadt looks to build on his strong win record despite a high ERA. Expect volatility from both starters in this rubber match.

Players to Watch

Cleveland Guardians

  • José Ramírez: .291 AVG, 26 HR, 66 RBI
  • Steven Kwan: 10 hits in last 41 ABs, 2 doubles, 1 HR
  • Bo Naylor: Emerging power threat behind the plate

Arizona Diamondbacks

  • Geraldo Perdomo: .289 AVG, 13 HR, 81 RBI
  • Ketel Marte: 13-for-39, 5 doubles, 2 HR in last 10 games
  • Corbin Carroll: Speed and pop combo, key leadoff spark

Betting Insights

Arizona’s slight edge reflects home-field advantage and Pfaadt’s win total, but Cleveland’s lineup could feast on his elevated ERA.

Game Odds

Cleveland Guardians      9

Arizona Diamondbacks – 115

Odds Courtesy of Sports Odd Direct as of Tuesday, August 19, 2025