MLB Game Preview: Cleveland Guardians (43-48) vs. Chicago White Sox (31-62)

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Game Details

  • Matchup: Cleveland Guardians (43–48) vs. Chicago White Sox (31–62)
  • Date: Thursday, July 10, 2025
  • Time: 7:40 PM ET
  • Venue: Guaranteed Rate Field, Chicago, IL
  • Broadcast: CHSN, CLEG, MLB.tv

Key Storylines

  • AL Central Clash: Both teams are struggling in the standings, but this four-game series opener offers a chance to reset momentum.
  • Guardians Slight Favorites: Cleveland enters as -136 moneyline favorites, having won 58% of games when favored this season.
  • Pitching Spotlight: Logan Allen (5–7, 4.07 ERA) starts for Cleveland against Jonathan Cannon (3–7, 4.50 ERA) for Chicago.

Starting Pitchers Breakdown

TeamPitcherW-LERAWHIPK/9Notes
GuardiansLogan Allen5–74.071.437.02 straight quality starts, 6 IP in 4 of last 6 outings
White SoxJonathan Cannon3–74.501.467.0Allowed 2 ER in last start vs. Rockies

Players to Watch

Cleveland Guardians

  • José Ramírez: .299 AVG, 16 HR, 44 RBI – hitting .333 over last 5 games with 3 HR.
  • Steven Kwan: .292 AVG, 20 doubles – elite contact hitter, consistent OBP.
  • Angel Martinez: .238 AVG, 6 HR – riding a 5-game hit streak, batting .316 over last 5.

Chicago White Sox

  • Miguel Vargas: .220 AVG, 10 HR, 34 RBI – leads team in all major offensive categories.
  • Andrew Benintendi: .240 AVG, 10 HR – slugging .415, reliable run producer.
  • Lenyn Sosa: .272 AVG, 7 HR – emerging bat with gap power.
  • Guardians are 7–3 when favored by -136 or more.
  • White Sox are 30–54 when listed at +114 or worse.
  • Under is trending: Both teams have hit the under in 8 of their last 10 combined games.

Cleveland has the edge on the mound and in recent form, especially with Ramírez heating up. Chicago’s offense remains inconsistent, and Cannon’s control issues could be exposed early. Expect a low-scoring battle with Cleveland pulling ahead late.

Game Odds

Cleveland Guardians      – 136

Chicago White Sox          8.5

Odds Courtesy of Sports Odd Direct as of Wednesday, July 9, 2025