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MLB Game Preview: Cleveland Guardians (25-18) vs. Cincinnati Reds (21-24)

The Cleveland Guardians (25-18) and Cincinnati Reds (21-24) are set to face off in the series opener at Great American Ball Park. The Guardians enter the matchup as slight favorites (-123 moneyline odds), while the Reds look to build momentum after a 7-1 victory over the White Sox in their last game.

Starting Pitchers

Cleveland Guardians – Tanner Bibee (RHP, 3-3, 3.80 ERA)

  • Bibee has been solid in his last five starts, averaging 5.6 innings per outing.
  • He has three quality starts this season and has held opponents to a .229 batting average.
  • In his most recent start against the Phillies, he pitched seven innings, allowing just one earned run.

Cincinnati Reds – Brady Singer (RHP, 4-2, 4.97 ERA)

  • Singer has been inconsistent, but he has the ability to limit damage when in rhythm.
  • He faces a Guardians lineup that ranks 12th in MLB in home runs (48) and has been effective in extra-base hits.

Key Players to Watch

Cleveland Guardians

  • José Ramírez (3B) – Batting .295 with eight home runs, currently on a nine-game hitting streak.
  • Steven Kwan (LF) – Leads the team with a .325 batting average, providing consistency at the top of the lineup.
  • Kyle Manzardo (1B) – Has 10 home runs this season, making him a power threat in the middle of the order.

Cincinnati Reds

  • Elly De La Cruz (SS) – Leads the Reds with eight home runs and 31 RBIs, hitting .286 over his last five games.
  • TJ Friedl (OF) – Batting .274 with six doubles and three home runs, providing speed and versatility.
  • Gavin Lux (2B) – Has a .291 batting average, making him one of Cincinnati’s most consistent hitters.

Game Strategy & Predictions

  • Guardians’ Game Plan:
    • Take advantage of Singer’s inconsistency by working deep counts.
    • Utilize Ramírez and Kwan’s ability to get on base to create scoring opportunities.
    • Bibee must limit hard contact, as the Reds rank 14th in slugging percentage (.385).
  • Reds’ Game Plan:
  • De La Cruz and Friedl need to set the tone early against Bibee.
  • Singer must avoid walks, as Cleveland has been effective at capitalizing on free passes.
  • Cincinnati’s bullpen must be ready, as Singer has struggled to go deep into games.

Game Odds

Cleveland Guardians      – 125

Cincinnati Reds                 9

Odds Courtesy of Sports Odds Direct as of Thursday, May 15, 2025

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