MLB Game Preview: Chicago White Sox (12-29) vs. Cincinnati Reds (20-22)

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Cincinnati Reds logo

The Chicago White Sox and Cincinnati Reds are set to face off in the first game of their series at Great American Ball Park in Cincinnati, Ohio. First pitch is scheduled for 6:40 PM ET.

Team Overview & Recent Form

Chicago White Sox (12-29, 5th in AL Central)

  • Last Five Games: Win, Loss, Win, Loss, Loss
  • Road Record: 3-17
  • Batting Average: .214 (29th in MLB)
  • Key Players:
  • Miguel Vargas – Eight doubles, two home runs, 12 RBIs, batting .215.
  • Luis Robert Jr. – Batting .270 with two home runs in his last 10 games.
  • Andrew Vaughn – Five home runs, 18 RBIs, batting .238.

Cincinnati Reds (20-22, 4th in NL Central)

  • Last Five Games: Loss, Win, Loss, Loss, Win
  • Home Record: 9-10
  • Batting Average: .238 (19th in MLB)
  • Key Players:
  • TJ Friedl – Batting .276 with six doubles, a triple, and three home runs.
  • Elly De La Cruz – Six home runs, 29 RBIs, providing power in the lineup.
  • Jose Trevino – Batting .313 over his last 10 games, with four doubles and two home runs.

Pitching Matchup

  • White Sox: Jonathan Cannon (RHP, 2-4, 4.10 ERA) – Has gone six innings or more in each of his last four starts, including three straight quality outings.
  • Reds: Andrew Abbott (LHP, 2-0, 2.25 ERA) – Has been dominant, holding opponents to a .186 batting average and averaging 11.6 strikeouts per nine innings.

Game Analysis & Predictions

  • White Sox’s Strategy: Chicago needs Cannon to deliver a strong outing while their offense capitalizes on Abbott’s occasional control issues.
  • Reds’ Strategy: Cincinnati has been strong at home and will rely on De La Cruz and Friedl to generate runs.

Game Odds

Chicago White Sox          9.5

Cincinnati Reds                 – 198

Odds Courtesy of Sports Odds Direct as of Monday, May 12, 2025