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MLB Game Preview: Boston Red Sox (40-38) vs. San Francisco Giants (43-34)

Game Details

  • Matchup: Boston Red Sox vs. San Francisco Giants
  • Date: Sunday, June 22, 2025
  • Time: 4:05 PM ET
  • Venue: Oracle Park, San Francisco, CA
  • Broadcast: ESPN, NESN, NBCS-BA, MLB.TV

Series Recap & Stakes

This is the final game of a three-game interleague series, with the series tied 1-1. The Red Sox took the opener 7-5, while the Giants bounced back with a 3-2 win on Saturday behind a clutch homer from Rafael Devers, who was recently traded from Boston to San Francisco.

Boston Red Sox – Team Snapshot

  • Record: 40-38 (4th in AL East)
  • Road Record: 18-21
  • Last 10 Games: 8-2
  • Key Players:
  • Jarren Duran: 84 hits, 14 SB – table-setter with speed
  • Wilyer Abreu: 13 HR – team’s top power bat
  • Ceddanne Rafaela: 28 RBI, 7 HR – versatile contributor

Starting Pitcher:
Lucas Giolito (3-1, 4.73 ERA) – The righty is coming off back-to-back shutout starts and owns a 1.93 ERA on the road this season.

San Francisco Giants – Team Snapshot

  • Record: 43-34 (2nd in NL West)
  • Home Record: 24-14
  • Last 10 Games: 4-6
  • Key Players:
  • Rafael Devers: 16 HR, 19 doubles – facing his former team
  • Heliot Ramos: .281 AVG, 13 HR – team’s most consistent bat
  • Wilmer Flores: 53 RBI – clutch run producer

Starting Pitcher:
Robbie Ray (8-2, 2.68 ERA) – The lefty has been dominant at home (2.29 ERA) and has a 2-2 career record vs. Boston with a 3.54 ERA.

Key Matchup Insights

  • Pitching Duel: Both starters are in strong form—expect a low-scoring affair.
  • Devers Drama: All eyes on Devers as he faces his former club for the third straight day.
  • Momentum Factor: Red Sox are 8-2 in their last 10, but the Giants have the edge at home.
  • Injury Watch: Boston is missing Alex Bregman, Triston Casas, and Masataka Yoshida; Giants are without Matt Chapman and Tom Murphy.

Game Odds

Boston Red Sox                 7.5

San Francisco Giants      – 164

Odds Courtesy of Sports Odds Direct as of Saturday, June 21, 2025

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