MLB Game Preview: Baltimore Orioles (63-76) vs. San Diego Padres (76-63)

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Venue, Date & Time

  • Date: Wednesday, September 3, 2025
  • First Pitch: 4:10 p.m. ET / 1:10 p.m. PT
  • Venue: PETCO Park, 100 Park Boulevard, San Diego, CA 92101
  • Surface: Natural Grass
  • Broadcast: MASN2 (Baltimore), SDPA (San Diego), MLB.TV

Weather Forecast (San Diego, CA – First Pitch)

  • Conditions: Mostly sunny
  • Temperature: ~77°F (25°C)
  • Wind: 6–8 mph from the northwest toward right field
  • Precipitation: 0% chance — no weather‑driven delays expected
  • Impact: Slight boost to balls hit to right; otherwise neutral hitting conditions

Injury Report

Baltimore Orioles

  • Cedric Mullins (OF) – 10‑Day IL (hamstring)
  • Anthony Santander (OF) – Day‑to‑day (wrist)
  • Tyler Wells (RHP) – 15‑Day IL (elbow)
  • John Means (LHP) – 60‑Day IL (elbow)
  • Félix Bautista (RHP) – 60‑Day IL (elbow surgery)

San Diego Padres

  • Jason Adam (RHP) – Out (quadriceps tendon rupture)
  • Xander Bogaerts (SS) – 10‑Day IL (shoulder)
  • Ha‑Seong Kim (INF) – 10‑Day IL (ankle)
  • Yu Darvish (RHP) – 15‑Day IL (neck)
  • Joe Musgrove (RHP) – 60‑Day IL (shoulder)

Probable Pitchers & Matchup

Baltimore – Cade Povich (LHP)

  • 2025 Stats: 2–7, 5.04 ERA, 1.46 WHIP, 100 K in 91.2 IP
  • Profile: 25‑year‑old lefty with a solid strikeout rate (9.9 K/9) but prone to hard contact (.274 opponent AVG).
  • Recent Form: 5.0 IP, 2 ER, 7 H vs. Boston in last start; 3 quality starts this season.

San Diego – Nestor Cortes (LHP)

  • 2025 Stats: 2–3, 5.06 ERA, 1.37 WHIP, 27 K in 32.2 IP
  • Profile: Deceptive left‑hander with a varied delivery; has struggled with consistency since returning from injury.
  • Recent Form: 3.0 IP, 3 ER vs. Minnesota in last start; 2 quality starts in 7 outings.

🔍 Key Player Matchups

Baltimore Orioles Offense

  • Gunnar Henderson (SS): .280 AVG, 16 HR, 61 RBI — team leader in HR and RBI.
  • Jackson Holliday (2B): .246 AVG, 19 2B, 15 HR — emerging young star with gap power.
  • Jeremiah Jackson (RF): .337 AVG, 8 HR in limited action — hot bat in recent weeks.

San Diego Padres Offense

  • Fernando Tatis Jr. (OF): .264 AVG, 18 HR, 57 RBI — dynamic power/speed threat.
  • Manny Machado (3B): .286 AVG, 21 HR, 79 RBI — veteran run producer.
  • Luis Arraez (DH): .282 AVG, 150 hits — elite contact hitter, tough to strike out.

Matchup Spotlight:

  • Povich’s ability to neutralize right‑handed bats (Machado, Tatis) will be key.
  • Cortes must navigate a lefty‑heavy Orioles lineup without giving up early crooked numbers.

Team Records & Recent Form

Recent Trends:

  • Baltimore: Won 2 of last 3; offense averaging 4.6 runs in that span.
  • San Diego: Lost 2 straight after 4‑game win streak; bullpen ERA 2.95 over last 10.

Series History

  • 2025 Season Series: Orioles lead 1–0 after 4–3 win on Sept. 1.
  • Last Meeting: Jeremiah Jackson HR, Dylan Beavers go‑ahead RBI single in 7th lifted Baltimore.
  • At PETCO Park: Orioles 3–2 in last 5 games.

Betting Trends

Baltimore Orioles

  • 33–42 as underdog (44% win rate)
  • 5–11 as +139 or longer
  • Over in 59 of 138 games (42.8%)

San Diego Padres

  • 44–29 as favorite (60.3% win rate)
  • 15–8 as -166 or shorter
  • Over in 59 of 138 games (42.8%)

Suggested Wagering Model

Model Inputs:

  • Both starters have ERAs over 5.00; potential for early scoring.
  • Padres’ bullpen stronger, but Orioles’ lineup in better recent form.
  • PETCO Park generally suppresses HRs, but warm weather + wind to right could aid lefty pull hitters.

Game Odds

Baltimore Orioles            8.5

San Diego Padres             – 166

Odds Courtesy of Sports Odds Direct as of Tuesday, September 2, 2025