MLB Game Preview: Baltimore Orioles (44-54) vs. Cleveland Guardians (48-50)

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Cleveland Guardians logo

Venue: Progressive Field, Cleveland, OH
First Pitch: 6:40 PM ET
Watch Live: MASN2, CLEG, MLB.TV

This four-game series could push Cleveland above .500 for the first time since late June. The Guardians are riding an 8–2 surge over their last 10 games, while Baltimore snapped a four-game skid with a win over Tampa Bay but remains inconsistent.

Baltimore took the earlier season series 2–1, outscoring Cleveland 18–9 in that set. However, the Guardians now have the easiest remaining strength of schedule in MLB, making this series a pivotal opportunity to build momentum.

Starting Pitchers – July 21, 2025

TeamPitcherRecordERAWHIPK/9
GuardiansTanner Bibee (RHP)5–94.291.247.8
OriolesTomoyuki Sugano (RHP)7–54.441.305.3
  • Tanner Bibee has struggled with command but owns better strikeout upside. He’s allowed 17 HRs and has a near-5.00 ERA at home.
  • Tomoyuki Sugano has been steady but vulnerable to the long ball (19 HRs allowed). He held Cleveland to 2 ER over 7 IP in April.

Players to Watch

Cleveland Guardians

  • José Ramírez: .295 AVG, 19 HR, 52 RBI; team leader in power and consistency
  • Steven Kwan: .285 AVG, 20 doubles, 6 HR; elite contact hitter
  • Angel Martinez: .246 AVG, 9 HR; batting .286 over last 5 games with 4 RBI

Baltimore Orioles

  • Gunnar Henderson: .280 AVG, 11 HR, 33 walks; versatile offensive weapon
  • Ryan O’Hearn: .282 AVG, 12 HR; team-high batting average
  • Jackson Holliday: 13 HR; emerging power bat
  • Cedric Mullins: 13 HR, 42 RBI; key run producer

Team Comparison – Key Stats

CategoryGuardiansOrioles
Batting Avg.223 (29th MLB).239 (23rd MLB)
Slugging %.370 (27th MLB).398 (16th MLB)
Home Runs102 (20th MLB)114 (12th MLB)
Runs/Game3.84.1
Team ERA3.964.75
Last 10 Games8–25–5

Game Odds

Baltimore Orioles            8

Cleveland Guardians      – 138

Odds Courtesy of Sports Odd Direct as of Sunday, July 20, 2025