MLB Game Preview: Arizona Diamondbacks (72-72) vs. San Francisco Giants (72-71)

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Venue & Game Details

  • First Pitch: 9:45 p.m. ET / 6:45 p.m. PT
  • Venue: Oracle Park, San Francisco, California
  • Series: Game 1 of a 3-game NL West series

Weather Forecast (San Francisco, CA)

  • Conditions: Partly cloudy
  • Temperature at First Pitch: ~66°F (19°C)
  • Wind: 8–12 mph from the west
  • Impact: Typical cool, marine-layer conditions at Oracle Park — could suppress long-ball distance.

Injury Report

Arizona Diamondbacks

  • Pavin Smith — 60-Day IL (quadriceps)
  • Lourdes Gurriel Jr. — 10-Day IL (ACL)
  • Kevin Ginkel — 60-Day IL (shoulder)
  • Tommy Henry — 60-Day IL (elbow)
  • Christian Montes De Oca — 60-Day IL (elbow)
  • Justin Martinez — 60-Day IL (elbow)
  • Cristian Mena — 60-Day IL (shoulder)
  • Corbin Burnes — 60-Day IL (elbow)
  • A.J. Puk — 60-Day IL (elbow)
  • Blake Walston — 60-Day IL (elbow)

San Francisco Giants

  • Randy Rodriguez — 60-Day IL (elbow)
  • Carson Whisenhunt — 15-Day IL (back)
  • Landen Roupp — 15-Day IL (knee)
  • Erik Miller — 60-Day IL (elbow)
  • Jerar Encarnacion — 10-Day IL (hamstring)
  • Tom Murphy — 60-Day IL (back)

Probable Pitchers

  • Diamondbacks: Nabil Crismatt (RHP) — 2–0, 2.14 ERA, 1.33 WHIP, 14 K
  • Giants: Logan Webb (RHP) — 13–9, 3.17 ERA, 1.23 WHIP, 194 K

Team Records & Recent Form

  • Diamondbacks: 34–38 on the road; 6th in NL in batting average (.250).
  • Giants: 35–34 at home; 3rd in NL in team ERA (3.77).

Series History

  • 2025 Season Series: Diamondbacks lead 4–3.
  • Last Meeting: Arizona took 2 of 3 in Phoenix.

Betting Trends

  • Giants are 9–5 this season when favored at -187 or shorter.
  • Diamondbacks are 2–2 when listed at +155 or longer.
  • Over has hit in 6 of Giants’ last 10 games; D-backs 4–6 to the over in that span.
  • Giants 8–2 ATS in their last 10 games.

Game Odds

Arizona Diamondbacks 7.5

San Francisco Giants      – 185

Odds Courtesy of Sports Odds Direct as of Sunday, September 7, 2025