FBS-CFB Game Preview: South Carolina State Bulldogs (2-1) vs. #18 South Florida Bulls (2-1)

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Kickoff: 9:00 AM ET
Venue: Raymond James Stadium, Tampa, Florida
Broadcast: ESPN+

Weather Forecast (Tampa, FL)

Temperature: ~82°F (28°C) at kickoff

Conditions: Hot and humid, partly cloudy skies, winds 6–9 mph

Impact: Classic Florida early-season conditions. Depth and hydration will be critical, especially for South Carolina State.

Injury Report

South Carolina State Bulldogs (MEAC, FCS):

QB Wynston Atkins IV (293 yards, 2 TDs through two games) healthy.

RB Keshawn Adams (65 rushing yards) available.

WR Javon Johnson (11 catches, 160 yards) healthy.

No major defensive absences reported, though depth is limited against FBS competition.

#18 South Florida Bulls (AAC, FBS):

QB Byrum Brown (473 passing yards, 1 TD; 109 rushing yards, 2 TDs) healthy and leading the offense.

WR Khalil Singleton (168 yards, 2 TDs) available.

RB rotation intact, with Brown himself a major rushing threat.

Defense healthy, led by LB Jhalyn Shuler.

Key Player Matchups

QB Wynston Atkins IV (SC State) vs. USF Secondary

Atkins has shown flashes but faces a top-25 defense with speed and depth.

WR Javon Johnson (SC State) vs. USF Corners

Johnson is SC State’s most reliable target; USF must prevent him from breaking big plays.

QB Byrum Brown (USF) vs. SC State Front Seven

Brown is a true dual-threat; SC State must contain his rushing lanes while respecting his passing ability.

WR Khalil Singleton (USF) vs. SC State Safeties

Singleton’s explosiveness makes him a game-changer; Bulldogs’ secondary will be tested vertically.

Series History

This is the first-ever meeting between South Carolina State and South Florida.

Betting Trends

South Florida:

2–0 ATS in 2025.

Unders hit in both games (defense-driven).

5–1 ATS in last 6 home games.

South Carolina State:

1–1 ATS in 2025.

Overs hit in 1 of 2 games.

0–5 SU in last 5 vs. FBS opponents.

Head-to-Head: No prior meetings.

Historical Betting Results

South Florida: Reliable ATS early in 2025, especially as a heavy favorite.

South Carolina State: Historically struggles ATS vs. FBS competition; often competitive early but fades late.

AAC vs. MEAC: AAC teams cover ~70% of the time in these matchups.

Game Odds

South Carolina State Bulldogs                    54.5

South Florida Bulls                                          – 38.5

Odds Courtesy of Sports Odd Direct as of Friday, September 19, 2025