Venue & Event Details
Location: Gaylord Family – Oklahoma Memorial Stadium, Norman, OK
Kickoff: 12:00 PM EST / 11:00 AM CST
Broadcast: ABC
Weather Forecast
Temperature: 54°F at kickoff, dropping into upper 40s by late afternoon
Conditions: Cloudy skies, winds 10–15 mph
Impact: Passing efficiency may be challenged; rushing and ball control favored
Injury Report
Missouri: QB Beau Pribula (healthy, 1,690 yards, 11 TDs, 7 INTs); RB Ahmad Hardy (healthy, 1,346 yards, 15 TDs); WR Kevin Coleman Jr. (healthy, 600 yards, 1 TD).
Oklahoma: QB John Mateer (healthy, 2,087 yards, 8 TDs, 7 INTs); RB Tory Blaylock (healthy, 404 yards, 4 TDs); WR Isaiah Sategna (healthy, 718 yards, 5 TDs).
Key Player Matchups
RB Ahmad Hardy (Missouri) vs Oklahoma Front Seven: Hardy’s power running (300 yards, 3 TDs vs Mississippi State last week) will test OU’s defense ranked 4th nationally in rush defense (82.2 YPG allowed).
QB John Mateer (Oklahoma) vs Missouri Secondary: Mateer’s efficiency (63.9% completion) faces a defense ranked 15th nationally in pass defense (169.9 YPG allowed).
WR Isaiah Sategna (OU) vs Missouri CBs: Sategna’s explosiveness (718 yards, 5 TDs) against a secondary that has allowed only 12 passing TDs all season.
Recent Team Forms
Missouri: Beat Mississippi State 49–27 (Nov. 15); Hardy rushed for 300 yards and 3 TDs.
Oklahoma: Beat Alabama 23–21 (Nov. 15); defense forced late turnovers to secure win.
Series History
Historic Rivalry: Former Big Eight and Big 12 foes.
Last meeting (2024): Missouri stunned Oklahoma 30–23 with a late defensive touchdown.
All-time: Oklahoma leads the series, but Missouri has won 2 of last 3.
Betting Trends:
Missouri is 5–5 ATS this season.
Oklahoma is 6–4 ATS.
Unders have hit in 3 of last 5 OU games.
Historical Betting Results
Oklahoma has covered in 4 of last 6 SEC games.
Missouri has covered in 3 of last 5 road games.
Underdogs have covered in 2 of last 3 Missouri–Oklahoma meetings.
Prediction: Oklahoma 27 – Missouri 21
Game Odds
Missouri Tigers 42.5
Oklahoma Sooners – 5.5
Odds Courtesy of Sports Odd Direct as of Friday, November 21, 2025
