FBS-CFB Game Preview: Mississippi Rebels (6-1) vs. Oklahoma Sooners (6-1)

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Venue & Game Info

Stadium: Gaylord Family – Oklahoma Memorial Stadium, Norman, OK

Kickoff: 12:00 PM ET (11:00 AM CT local)

Broadcast: ABC (national)

Weather Forecast: Sunny, 64°F at kickoff, light winds (5–7 mph), no precipitation expected – ideal conditions for a high-level SEC clash.

Team Recent Form

Ole Miss Rebels:

Last game: 43-35 loss at Georgia – blew a 4th-quarter lead.

Offense: 37.4 PPG (Top 15 nationally), 491.9 YPG (8th nationally)

Defense: 27.1 PPG allowed (bottom half nationally)

Strength: Explosive passing game led by QB Trinidad Chambliss.

Oklahoma Sooners:

Last game: 26-7 win at South Carolina – dominant defensive showing.

Offense: 29.7 PPG, 410 YPG – efficient but not explosive.

Defense: 9.4 PPG allowed (2nd nationally), 3.68 YPP allowed (1st nationally)

Strength: Elite defensive front, suffocating pass rush.

Injury Report

Ole Miss: No major injuries reported.

Oklahoma: WR Jalil Williams (undisclosed) – questionable; DB Kaden Simmons (undisclosed) – questionable.

Key Player Matchups

QB Trinidad Chambliss (Ole Miss): 1,850 yards, 14 TD, 4 INT – first Rebel QB since Eli Manning to throw for 250+ yards in each of first five starts.

QB John Mateer (Oklahoma): 1,600 yards, 12 TD, 3 INT, plus 5 rushing TDs – dual-threat efficiency.

Ole Miss WR De’Zhaun Stribling vs. OU CB Gentry Williams: Stribling leads Rebels in receiving yards; Williams anchors OU’s secondary.

OU DL R Mason Thomas vs. Ole Miss OL: Thomas leads Sooners in sacks; Rebels’ O-line has struggled against elite fronts.

Series History

First-ever SEC meeting between Ole Miss and Oklahoma.

Historically, Oklahoma is 3-0 vs. Ole Miss in bowl/playoff-era exhibitions, but this is their first conference clash.

Betting Trends

Ole Miss: 4-1 in one-score games this season; 2-2 ATS on the road.

Oklahoma: All 7 games have gone UNDER the total by an average of 11 points.

Head-to-Head: No recent SEC history, but OU has covered in 5 of last 6 home games vs. ranked opponents.

Historical Betting Results: Ole Miss 3-4 ATS in 2025; Oklahoma 5-2 ATS.

Projection: Oklahoma 27 – Ole Miss 20

Game Odds

Mississippi Rebels          52.5

Oklahoma Sooners         – 5.5

Odds Courtesy of Sports Odd Direct as of Friday, October 24, 2025