Venue & Event Details
Location: Gerald J. Ford Stadium, University Park (Dallas), TX
Kickoff: 12:00 PM EST / 11:00 AM CST
Broadcast: ESPN2
Weather Forecast
Temperature: 63°F at kickoff, rising to 68°F by mid-afternoon
Conditions: Sunny skies, light winds (5–8 mph)
Impact: Ideal conditions for both passing and rushing
Injury Report
Louisville: QB Miller Moss (healthy, 2,344 yards, 11 TDs, 7 INTs); RB Isaac Brown (782 yards, 5 TDs); WR Chris Bell (871 yards, 6 TDs). No major injuries reported.
SMU: QB Kevin Jennings (healthy, 2,810 yards, 21 TDs, 9 INTs); RB Tomarion Harden (612 yards, 6 TDs); WR Jordan Hudson (595 yards, 4 TDs). WR Romello Brinson (582 yards, 3 TDs) probable.
Key Player Matchups
Kevin Jennings (SMU QB) vs Louisville Secondary: Jennings’ efficiency (64.8% completion) will test a defense that allowed 20 points in a narrow loss vs Clemson.
Miller Moss (Louisville QB) vs SMU Defense: Moss’s ability to avoid turnovers will be critical against an SMU defense that thrives on pressure.
Chris Bell (Louisville WR) vs SMU CBs: Bell’s big-play ability (871 yards, 6 TDs) against a secondary that has allowed multiple 300-yard passing games.
Recent Team Forms
Louisville: Lost 20–19 vs Clemson (Nov. 14); previously beat Virginia Tech 28–16 and lost 29–26 vs California.
SMU: Beat Boston College 45–13 (Nov. 8); beat Miami (FL) 26–20 (Nov. 1); lost 13–12 vs Wake Forest (Oct. 25).
Series History
All-time: SMU leads 1–0 (beat Louisville in 2024).
Last meeting: SMU won 31–24 in Dallas.
Betting Trends:
Louisville is 4–6 ATS this season.
SMU is 6–4 ATS.
Overs have hit in 3 of last 5 SMU games.
Historical Betting Results
SMU has covered in 4 of last 6 ACC games.
Louisville has failed to cover in 3 of last 5 ACC games.
SMU has won 3 of last 4 home games.
Prediction: SMU 31 – Louisville 27
Game Odds
Louisville Cardinals 49.5
SMU Mustangs – 4
Odds Courtesy of Sports Odd Direct as of Friday, November 21, 2025
