Venue & Game Info
Kickoff: 4:00 PM ET / 3:00 PM CT
Location: Centennial Bank Stadium, Jonesboro, Arkansas
Broadcast: ESPN2 Streaming: ESPN app
Notable: First Big 12 program and highest-ranked opponent ever to visit Centennial Bank Stadium
Weather Outlook
Forecast: Sunny, hot, and humid
Temperature at Kickoff: ~97°F, “feels like” over 100°F
Winds: 5–8 mph from the southwest
Impact: Heat could test depth and conditioning; hydration and rotation management will be critical
Injury & Availability Report
Iowa State:
OL Trevor Buhr — Probable (returning from injury)
LB Carson Willich — Questionable
LB Cael Brezina — Expected to play after minor knock vs. Iowa
Overall roster health described by HC Matt Campbell as “as good as we’ve been at this point in the season”
Arkansas State:
No major starters ruled out
QB Jaylen Raynor fully fit; leads team in both passing and rushing yards
Young defensive unit — 10 first-time starters this season
Recent Form
Iowa State:
W 16–13 vs. Iowa — won Cy-Hawk rivalry on late 54-yard FG
W 52–7 vs. Arkansas State (2024) — dominant in last year’s meeting
W 38–14 vs. Kansas State (in Dublin) — season opener
Arkansas State:
L 56–14 at Arkansas — offense stalled, defense gashed on ground
W 38–14 vs. FCS opponent — efficient passing, opportunistic defense
Series History
All-Time: Iowa State leads 1–0
Last Meeting: 2024 — Iowa State 52, Arkansas State 7 in Ames
Note: This is the return leg of a home-and-home series
Betting Trends
Iowa State: 2–1 ATS in 2025; Under in 2 of 3 games
Arkansas State: 1–1 ATS in 2025; Over in 1 of 2 games
Totals: Model leans Under based on ISU’s defensive metrics and ASU’s offensive inconsistency
Game Odds
#16 Iowa State Cyclones – 21.5
Arkansas State Red Wolves 55.5
Odds Courtesy of Sports Odd Direct as of Friday, September 12, 2025
