FBS-CFB Game Preview: #11 South Carolina Gamecocks (2-1) vs. #25 Missouri Tigers (3-0)

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Kickoff: 7:00 PM ET
Venue: Memorial Stadium/Faurot Field, Columbia, Missouri
Broadcast: ESPN

Weather Forecast (Columbia, MO)

Temperature: ~75°F (24°C) at kickoff

Conditions: Clear skies, light winds (5–8 mph)

Impact: Perfect football weather; no disruptions expected for passing or kicking.

Injury Report

South Carolina Gamecocks (SEC East):

QB Luke Doty (148 yards, 1 INT vs. Vanderbilt) healthy but under pressure to rebound.

RB Rahsul Faison (74 yards, 1 TD vs. Vanderbilt) available.

WR Nyck Harbor (66 yards vs. Vanderbilt) healthy.

No major defensive absences reported.

Missouri Tigers (SEC East):

QB Beau Pribula (174 yards, 2 TD, 1 INT vs. Louisiana) healthy and efficient.

RB Ahmad Hardy (250 yards, 3 TDs vs. Louisiana) available and in top form.

WR Kevin Coleman Jr. (8 catches, 84 yards vs. Louisiana) healthy.

Defense intact, led by LB Daylan Carnell.

Key Player Matchups

QB Luke Doty (South Carolina) vs. Missouri Secondary

Doty has struggled with turnovers; Missouri’s defense has been opportunistic.

RB Rahsul Faison (South Carolina) vs. Missouri Front Seven

Faison must establish the run to keep Missouri’s offense off the field.

QB Beau Pribula (Missouri) vs. South Carolina Pass Rush

Pribula has been efficient; Gamecocks must pressure him to force mistakes.

RB Ahmad Hardy (Missouri) vs. South Carolina Linebackers

Hardy’s 11.4 yards per carry last week makes him the X-factor.

Recent Team Form

South Carolina Gamecocks (2–1, ranked #11)

8/30/25: W 31–14 vs. Old Dominion

9/6/25: W 27–20 vs. Appalachian State

9/13/25: L 31–7 vs. Vanderbilt

Trend: Defense solid, but offense inconsistent and turnover-prone.

Missouri Tigers (3–0, ranked #25)

8/30/25: W 34–17 vs. Memphis

9/6/25: W 27–21 @ Kansas State

9/13/25: W 52–10 vs. Louisiana

Trend: Offense explosive, defense stout; undefeated start has vaulted them into the Top 25.

Series History

Missouri leads the all-time series 8–5.

Missouri has won five straight meetings (2019–2024).

Last year (2024): Missouri defeated South Carolina 34–12 in Columbia, SC.

Betting Trends

Missouri:

3–0 ATS in 2025.

Overs hit in all 3 games.

Strong ATS record at home when favored by double digits.

South Carolina:

1–2 ATS in 2025.

Unders hit in all 3 games.

Struggled to cover large spreads on the road.

Head-to-Head:

Missouri 5–0 SU and ATS in last five meetings.

Historical Betting Results

Missouri: Reliable ATS at home, especially as a favorite.

South Carolina: Historically struggles ATS vs. Missouri, particularly in Columbia.

SEC Trends: SEC East divisional games often trend under, but Missouri’s 2025 offense has pushed totals higher.

Game Odds

South Carolina Gamecocks          46.5

Missouri Tigers                                 – 13.5

Odds Courtesy of Sports Odd Direct as of Friday, September 19, 2025