The Philadelphia Eagles travel to face the Buffalo Bills in a high-stakes interconference matchup with playoff implications for both teams. The Eagles, sitting atop the NFC East, look to solidify their seeding, while the Bills aim to maintain their strong position in the AFC East race. This game features two explosive offenses led by dual-threat quarterbacks and could preview a potential Super Bowl matchup.
Venue Location
Highmark Stadium, Orchard Park, New York.
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The outdoor stadium, known for its passionate fans and potential for inclement weather, has a capacity of approximately 71,000 and is located just outside Buffalo.
Kickoff is set for 4:25 p.m. ET.
Broadcast: FOX: Kevin Burkhardt, Tom Brady, Erin Andrews (field reporter), Tom Rinaldi (field reporter), streaming on
Fubo (for in-market viewers) and NFL+.
Weather Updates
Forecast for game time in Orchard Park calls for chilly conditions with temperatures around 36-37°F, winds up to 13 mph from the northwest, and a 55% chance of precipitation (possible light snow or rain).
Cloud cover is expected to be minimal earlier in the day but could increase. These conditions favor a ground-heavy game plan, potentially impacting passing attacks and favoring defenses. No major storm systems are anticipated, but monitor updates as lake-effect weather can shift quickly in the region.
Injury Report
Both teams enter with key players banged up, but core stars appear likely to suit up. Here’s a breakdown based on the latest reports as of December 24:
Philadelphia Eagles:
OT Lane Johnson (foot): Questionable – Did not participate in early week practices; critical for protecting QB Jalen Hurts.
DT Jalen Carter (shoulder): Questionable – Limited in practice; his absence would weaken the interior run defense.
TE Cameron Latu (neck): Questionable – Recently added; depth piece but could affect two-tight end sets.
QB Jalen Hurts: No injury designation – Played through recent games without issues, though monitored for any lingering effects from earlier in the month.
Others: OT Cameron Williams (foot) and several depth players are out or limited, but no major additional stars ruled out.
Buffalo Bills:
QB Josh Allen (undisclosed/rest): Expected to play – DNP in early walkthrough but described as “day-to-day” and upbeat about availability; he’s 0-2 lifetime vs. Eagles.
DT Jordan Phillips (ankle): Questionable – Ruled out last week; key rotational lineman.
DT DaQuan Jones (calf): Questionable – Managing ongoing issue; impacts run stuffing.
S Jordan Poyer (undisclosed): Questionable – Veteran presence in secondary.
Others: Kicker situation stable (no major issues noted), but depth DTs like Jordan Phillips could force adjustments if out.
Injuries could tilt the trenches in favor of the healthier side, with Eagles’ O-line concerns potentially exposing Hurts to Buffalo’s pass rush.
Player Matchups
This game hinges on several elite battles:
QB Jalen Hurts (Eagles) vs. QB Josh Allen (Bills): A marquee dual-threat showdown. Hurts has thrown for multiple TDs in recent wins, while Allen leads the NFL in total TDs (rushing/passing). Expect both to extend plays with their legs.
RB Saquon Barkley (Eagles) vs. Bills Run Defense: Barkley is chasing rushing records with 132 yards in his last outing; Bills allow 121.7 rush yards per game (15th in NFL).
RB James Cook (Bills) vs. Eagles Run Defense: Cook tops the league with 158.9 rush yards per game; Eagles’ D has tightened, allowing just 40 points over the last three games.
Eagles Secondary vs. Bills WRs (e.g., Khalil Shakir, Keon Coleman): Philly’s pass D ranks 23rd (197.9 yards allowed); Bills’ aerial attack averages 214.2 yards (18th).
Bills O-Line vs. Eagles Pass Rush: If Carter plays, he could exploit Buffalo’s interior; otherwise, Allen gets more time.
Advantage leans to the QBs’ mobility in cold weather.
Recent Team Forms
Both teams are surging into the playoffs.
Philadelphia Eagles (Last 5 Games):
Dec 20 vs. Washington: W 29-18 (Hurts 2 TD passes, Barkley 132 rush yards).
Prior: Wins in 4 of last 5, including dominant performances vs. LAR (33-26), TB (31-25), but a loss to DEN (17-21). Overall streak: W-W-W-L-W. Defense allowing under 20 points in recent wins.
Buffalo Bills (Last 5 Games):
Dec 21 vs. Opponent (recent log implies win, part of 11-4 run).
Prior: Wins in 4 of last 5, with high-scoring outputs (e.g., 39 points in a home game). Streak: W-L-W-W-W. Offense firing on all cylinders, averaging 389.5 total yards per game.
Eagles are 7-3 in their last 10; Bills 8-2.
Series History
The Eagles lead the all-time series 9-6.
Last meeting: Eagles 37-34 OT win in 2023 (Hurts 5 total TDs).
Bills’ last victory: 31-24 in 2011. Philly has won the last three encounters, but Buffalo is 4-3 at home in the series. Allen is 0-2 vs. Eagles.
Betting Trends
Eagles: 8-7 ATS overall, 6-2 ATS as underdogs. They’ve covered in 4 of last 5 road games. Over has hit in 7 of 15 games.
Bills: 7-8 ATS, but just 5-8 as favorites. 4-1 straight up in last 5, but 2-3 ATS. Over has hit in 9 of 15 games, especially at home (5-3).
Head-to-Head: Last 3 games went over the total; Eagles 3-0 ATS vs. Bills since 2015.
EAGLES NOTES:
• EAGLES clinched NFC East for 2nd straight season, 1st NFC East team to win division in back-to-back seasons in 21 years (Phi. in 2001-04). • QB JALEN HURTS passed for 185 yards & 2 TDs for 111.1 rating & added 40 rush yards in Week 16. Had TD pass in 4 of his past 5 & TD pass in 6 of his past 7 on road. Passed for 200 yards & 3 TDs & had 2 rush TD in last meeting. • RB SAQUON BARKLEY had team-high 132 rush yards & TD in Week 16. Aims for 4th in row with rush TD. Has 100+ scrimmage yards in 3 of his past 4 on road. Ranks 3rd in NFL with 10,939 scrimmage yards since 2018. Aims for 3rd in row vs. Buf. with 95+ scrimmage yards (w/ NYG). • WR A.J. BROWN led team with 95 rec. yards in Week 16 & has 95+ rec. yards in 4 of his past 5 games on road. Had rec. TD in last meeting. • WR DEVONTA SMITH had TD reception in Week 16. Had 106 rec. yards & TD in last meeting. • TE DALLAS GOEDERT had TD catch in Week 16 & aims for 3rd in row with TD reception. Ranks tied-1st among TEs with 10 TD receptions this season. • LB ZACK BAUN had team-high 9 tackles in Week 16 & has 7+ tackles in 6 of his past 7 games. Has career-high 2 INTs this season. • LB NAKOBE DEAN has sack in 3 of his past 4 on road. • DE BRANDON GRAHAM had sack in Week 16 & aims for 3rd in row with sack & 3rd in row vs. Buf. with sack. • DT JORDAN DAVIS had 6 tackles & 2 TFL in Week 16. Has 2+ TFL in 2 of his past 3 games. Aims for 4th in row on road with TFL. • DT BYRON YOUNG had sack in Week 16 & aims for 3rd in row on road with sack. • DB COOPER DEJEAN had INT & career-high 4 PD in Week 16. Aims for 4th in row on road with PD. • CB ADOREE’ JACKSON has PD in 2 of his past 3 games. • S REED BLANKENSHIP had 10 tackles in last meeting.
BILLS NOTES:
• BILLS clinched 7th-consecutive playoff berth. Lead AFC in total offense (373.1 yards per game) & scoring offense (28.9 points per game). • QB JOSH ALLEN completed 12 of 19 atts. (63.2 pct.) for 130 yards in Week 16. Surpassed Tom Brady & Russell Wilson for 2nd-most reg. season wins by QB in 1st 8 seasons (87). Needs TD to become youngest in age & fastest in games played to reach 300 career offensive TDs. Has 60+ comp. pct., 205+ pass yards, TD pass & 100+ rating in each of his 7 home starts this season. Passed for 339 yards & 2 TDs & rushed for 81 yards & 2 TDs in last meeting. • RB JAMES COOK led team with 134 scrimmage yards (117 rush, 17 rec.) & had 2 rush TDs last week. Aims for his 3rd in row with 2+ scrimmage TDs. Has 110+ scrimmage yards in 11 games this season, most in NFL, incl. in 8 of his past 9. Had 6 catches & 100 scrimmage yards (57 rec., 43 rush) in last meeting. • RB TY JOHNSON had rush TD in Week 16. • DE GREG ROUSSEAU had 2.5 sacks in Week 16. Aims for his 3rd in row with sack. Had 4 tackles, 3 TFL & FR in last meeting. • DE JOEY BOSA had PD last week. Aims for his 3rd in row with PD. Had sack in his last game vs. Phi. (11/7/21 w/ LAC). • DT DAQUAN JONES had 4 tackles & 1st-career INT in Week 16. • DT DEONE WALKER (rookie) had 3 tackles & 2 PD last week. • LB MATT MILANO had 9 tackles & TFL in Week 16. Has TFL in 4 of his past 5. Aims for his 4th in row with 5+ tackles. Had 13 tackles & 3 TFL in last meeting. • CB TRE’DAVIOUS WHITE had 4 tackles & PD last week. Has PD in 4 of his past 5. • S JORDAN POYER led team with 11 tackles & had 1st INT of season & half sack in Week 16. Aims for his 10th in row with 5+ tackles. Had 6 tackles & PD in last meeting. • S COLE BISHOP had 7 tackles & TFL last week. Aims for his 4th in row with 5+ tackles.
Game Odds
Philadelphia Eagles 43.5
Buffalo Bills – 1.5
Odds Courtesy of Sports Odd Direct as of Saturday, December 27, 2025
