Venue & Event Details
Location: Kinnick Stadium, Iowa City, Iowa
Kickoff: 3:30 PM EST
Broadcast: FS1
Weather Forecast
Temperature: Mid-40s °F at kickoff, dropping into upper 30s by evening
Conditions: Cloudy skies, winds 10–15 mph
Impact: Passing efficiency may be challenged; rushing attacks and red-zone execution will be critical
Injury Report
Michigan State: QB Aidan Chiles (probable, minor shoulder soreness); WR Nick Marsh (healthy, team’s leading receiver with 559 yards, 5 TDs).
Iowa: QB Mark Gronowski (healthy, 1,216 yards, 6 TDs, 5 INTs); RB Kamari Moulton (healthy, 612 yards rushing).
Key Player Matchups
QB Aidan Chiles (MSU): 1,392 yards, 10 TDs, 3 INTs vs Iowa defense ranked 6th nationally in pass defense (157.4 yards allowed per game).
RB Kamari Moulton (Iowa): 612 yards, 2 TDs vs MSU rush defense allowing 153.9 yards per game.
WR Nick Marsh (MSU): 559 yards, 5 TDs vs Iowa CB unit that has held opponents to under 160 passing yards per game.
Turnovers: MSU ranks 101st nationally with a -4 margin; Iowa ranks 40th with a +3 margin.
Recent Team Forms
Michigan State: Lost 28–10 to Penn State on Nov. 15; offense struggled with only 128 passing yards.
Iowa: Lost 26–21 to USC on Nov. 15; Gronowski threw for 132 yards, 1 TD, 1 INT.
Series History
All-time: Iowa leads the series 24–22.
Recent trend: Michigan State upset Iowa 32–20 in 2024, their only win in a seven-game stretch.
At Kinnick Stadium: Iowa has won 3 of last 4 meetings.
Betting Trends:
Iowa is 4–2 ATS in last 6 games.
Michigan State is 2–5 ATS in Big Ten play.
Unders have hit in 4 of Iowa’s last 6 games.
Historical Betting Results
Iowa has covered in 3 of last 4 home games.
Michigan State has failed to cover in 4 of last 5 road games.
Totals have gone under in 3 of last 4 head-to-head meetings.
Projected Score: Iowa 24 – Michigan State 10
Game Odds
Michigan State Spartans 42.5
Iowa Hawkeyes – 17.5
Odds Courtesy of Sports Odd Direct as of Friday, November 21, 2025
