NBA Game Preview: Cleveland Cavaliers (0-0) vs. New York Knicks (0-0)

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Venue & Tipoff

Arena: Madison Square Garden, 4 Pennsylvania Plaza, New York, NY 10001

Tipoff: 7:00 p.m. ET

Broadcast: ESPN, MSG Network

Injury Report

Cavaliers:

Darius Garland (toe) – Out

De’Andre Hunter (knee) – Questionable

Sam Merrill (undisclosed) – Questionable

Knicks:

Karl-Anthony Towns (quadriceps) – Questionable

O.G. Anunoby (ankle) – Questionable

Josh Hart (back) – Out

Mitchell Robinson (ankle management) – Out

Player Matchups

Backcourt Battle: Jalen Brunson vs. Donovan Mitchell – two elite scoring guards who dictate tempo.

Frontcourt Clash: Karl-Anthony Towns (if active) vs. Evan Mobley – stretch big vs. defensive anchor.

Wings: Mikal Bridges & OG Anunoby vs. Isaac Okoro & De’Andre Hunter – perimeter defense and spacing will be decisive.

Team Records & Recent Form

Cavaliers (2024–25): 64–18, 41–11 in East play. Averaged 121.9 PPG (NBA-best).

Knicks (2024–25): 51–31, 34–18 in East play. Averaged 115.8 PPG, strong home record (27–14).

Recent Meetings (2024–25): Cleveland dominated, winning 3 of 4, including a 142–105 blowout in February.

Series History

Last 5 matchups: Cavaliers 4–1.

Knicks’ last win: March 2024 (107–98).

MSG has been a tough venue historically, but Cleveland’s offense has traveled well.

Betting Trends:

Knicks 40–41–1 ATS last season; 56% of home games went Over.

Cavaliers 47–33–2 ATS; 50 of 82 games went Over.

Combined scoring last season: 237.7 PPG, well above this total.

Game Odds

Cleveland Cavaliers        – 1.5

New York Knicks               227.5

Odds Courtesy of Sports Odds Direct as of Tuesday, October 21, 2025