NHL Game Preview: Detroit Red Wings (5-1-0) vs. Buffalo Sabres (2-4-0)

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Venue & Start Time

Arena: KeyBank Center, 1 Seymour H. Knox III Plaza, Buffalo, NY 14203

Puckdrop: 7:30 p.m. ET

Broadcast: TNT (U.S.), Sportsnet (Canada), streaming on HBO Max/Fubo

Injury Report

Detroit Red Wings:

Patrick Kane (upper body) – Day-to-day

Nate Danielson (undisclosed) – Out

Shai Buium (IR) – Out

Buffalo Sabres:

Ukko-Pekka Luukkonen (lower body) – Out

Josh Norris (upper body) – Out until December

Jordan Greenway (lower body) – Out

Michael Kesselring (lower body) – Out until Nov. 1

Justin Danforth (lower body) – Out until mid-November

Jacob Bryson (upper body) – Day-to-day

Player Matchups

Dylan Larkin (DET, 11 pts) vs. Zach Benson (BUF, 6 pts): Larkin’s hot start drives Detroit’s offense, while Benson is Buffalo’s top playmaker.

Lucas Raymond (DET) vs. Jason Zucker (BUF): Both wingers provide secondary scoring threats.

Moritz Seider (DET) vs. Rasmus Dahlin (BUF): Elite young defensemen anchoring their blue lines.

Goaltending: Cam Talbot (DET, 3–0–0, 1.78 GAA, .932 SV%) vs. Alex Lyon (BUF, 2–4–0, 2.55 GAA, .924 SV%).

Team Recent Form

Detroit Red Wings:

Goals per game: 3.33

Goals allowed: 2.33 (4th in NHL)

Power play: 22.2%

Penalty kill: 92.3% (4th)

Last 5: W vs. EDM 4–2, W vs. TB 2–1 (OT), W vs. FLA 4–1, W @ TOR 3–2, W vs. TOR 6–3

Buffalo Sabres:

Goals per game: 2.50

Goals allowed: 3.00

Power play: 26.3% (6th)

Penalty kill: 95.8% (2nd)

Last 5: L @ MTL 4–2, W vs. FLA 3–0, W vs. OTT 8–4, L vs. COL 3–1, L @ BOS 3–1

Series History

2024–25 season: Detroit won series 3–1.

Red Wings have won 5 of the last 6 meetings.

Buffalo’s last home win vs. Detroit: March 2023.

Betting Trends:

Detroit is 5–0 ATS in last 5 games.

Buffalo is 2–2 at home this season.

The Under has hit in 3 of Detroit’s last 4 games.

Detroit has won 5 of last 6 head-to-head matchups.

Game Odds

Detroit Red Wings           – 112

Buffalo Sabres                   6.5

Odds Courtesy of Sports Odds Direct as of Tuesday, October 21, 2025