NFL Game Preview: Green Bay Packers (3-1-1) vs. Arizona Cardinals (2-4)

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Venue & Game Info

Location: State Farm Stadium, Glendale, AZ

Kickoff: Sunday, Oct. 19, 2025 – 4:25 p.m. ET (1:25 p.m. MST)

Broadcast: FOX: Kenny Albert, Jonathan Vilma, Jen Hale (field reporter)

Surface: Retractable roof turf

Weather Forecast

Temperature: ~85°F (roof likely closed)

Conditions: Clear skies, minimal wind

Impact: None — ideal passing conditions indoors

Injury Report

Packers

WR Christian Watson (knee) – Out

DL Devonte Wyatt (knee) – Out

OL Zach Tom (oblique/back) – Questionable

K Brandon McManus (quad) – Questionable

G Aaron Banks (groin/knee) – Limited

RB Josh Jacobs (illness) – Limited

Cardinals

QB Kyler Murray (foot) – Questionable

WR Marvin Harrison Jr. (concussion) – Limited

WR Zay Jones (knee) – Out

RB Emari Demercado (ankle) – DNP

RB Zonovan Knight (knee) – Limited

DL Darius Robinson (pectoral) – Out

Player Matchups

Jordan Love (GB) vs. Cardinals Secondary: Love (1,259 yds, 9 TD, 2 INT) faces a defense allowing 246 pass yds/game (28th in NFL).

Josh Jacobs (GB) vs. Cardinals Run Defense: Jacobs (359 yds, 6 TD) provides balance against Arizona’s 102 rush yds allowed/game.

Kyler Murray/Jacoby Brissett (ARI) vs. Packers Defense: Murray’s status looms large; Brissett threw for 320 yds last week but lacks Murray’s explosiveness.

Trey McBride (ARI) vs. Packers Linebackers: McBride (347 yds, 2 TD) is Arizona’s most reliable target.

Micah Parsons (GB) vs. Cardinals O-Line: Parsons has transformed Green Bay’s pass rush; Arizona has allowed 14 sacks in 6 games.

Team Recent Form

Packers (3-1-1): Beat Bengals 27-18 in Week 6; only loss to Browns, tie vs. Cowboys. Defense ranks 5th in yards allowed (280.2/game).

Cardinals: Four straight losses, most recently 31-27 vs. Colts. Offense averaging 21.7 PPG but plagued by late-game collapses.

Series History

All-time: Packers lead 47–26–4

Last Meeting: Packers won 34-13 (Oct. 2024)

Notable: Cardinals upset Packers in 2009 and 2015 playoff thrillers

Betting Trends

Packers are 2-3 ATS this season; 0-2 ATS on the road

Cardinals are 3-3 ATS, but 0-3 ATS at home

Under is 3-1-1 in Packers games; Cardinals split 3-3 on totals

Packers are 8-4 ATS in last 12 vs. Arizona

Projection: Packers 27, Cardinals 20

PACKERS NOTES:

• QB JORDAN LOVE passed for 259 yards & TD vs. INT for 101.3 rating in Week 6. Has 100+ rating in 4 of his past 5. Ranks 5th in NFL with 110.9 rating. Passed for 258 yards & 4 TDs vs. INT for 119.5 rating in last meeting. Has 36 TDs (33 pass, 3 rush) in 19 career reg. season road starts. • RB JOSH JACOBS had 150 scrimmage yards (93 rush, 57 rec.) & 2 rush TDs in Week 6 & aims for his 3rd in row with 150+ scrimmage yards & 2 rush TDs. Has 6 rush TDs in 2025 & became 4th RB since 2000 with 6+ rush TDs in each of his 1st 7 seasons. Has 11 rush TDs in his past 8 on road. Aims for his 3rd in row vs. Ari. with 75+ scrimmage yards. • WR MATTHEW GOLDEN (rookie) had career highs in scrimmage yards (102) & rec. yards (86) in Week 6. Aims for his 4th in row with 60+ rec. yards. • WR ROMEO DOUBS aims for his 3rd in row with 5+ catches & 50+ rec. yards. Has 5 rec. TDs in his past 4 on road. Had 2 rec. TDs in last meeting. • TE TUCKER KRAFT had 3rd rec. TD of season last week. • DE MICAH PARSONS had sack in his last game vs. Ari. (9/24/23 w/ Dal.) & aims for his 3rd in row vs. Ari. with TFL. • DE RASHAN GARY has 5 sacks & 6 TFL in his past 6 on road. • DE LUKAS VAN NESS had 1st full sack of season in Week 6. • LB EDGERRIN COOPER led team with 11 tackles & had 1st TFL of season in Week 6. Aims for his 3rd in row on road with PD. • LB QUAY WALKER aims for his 3rd in row on road with 11+ tackles & 6th in row with 8+ tackles. Had 11 tackles & TFL in last meeting. • CB KEISEAN NIXON aims for his 3rd in row with 2 PD. Leads NFC & ranks 2nd in NFL with 9 PD in 2025. • CB CARRINGTON VALENTINE had 1st PD of season last week. • S JAVON BULLARD has TFL in 2 of his past 3. • S EVAN WILLIAMS had TFL last week. Had FF in last meeting.

CARDINALS NOTES:

• QB KYLER MURRAY has 20 TDs (16 pass, 4 rush) in his past 12 home starts. Has 90+ rating in 4 of his past 5 at home. Has TD pass in 4 of his 5 games in 2025. Passed for 214 yards & TD vs. 0 INTs for 97.7 rating in last meeting. • QB JACOBY BRISSETT passed for 320 yards & 2 TDs vs. INT for 89.2 rating in Week 6, his 7th-career game with 300+ pass yards. • RB BAM KNIGHT had 54 scrimmage yards (34 rush, 20 rec.) & 3rd-career rush TD last week. Aims for his 3rd in row with rush TD. • RB MICHAEL CARTER had 64 scrimmage yards (34 rush, 30 rec.) in Week 6. Has 50+ scrimmage yards in 4 of his past 5 & aims for his 3rd in row with 60+ scrimmage yards. • TE TREY MCBRIDE had season-high 8 catches for 72 yards & 2nd rec. TD of season in Week 6, his 8th-career TD catch. Ranks 2nd among TEs in receptions (37) & rec. yards (347) in 2025. Is 1 of 2 (Christian McCaffrey) with 5+ catches in 6 games this season. Has 258 career catches & can surpass HOFer Antonio Gates (265) for 2nd-most by TE in 1st 4 seasons all-time. • WR GREG DORTCH had 1st rec. TD of season last week. • WR MARVIN HARRISON JR. aims for his 3rd in row at home with 65+ rec. yards. • LB MACK WILSON had 9 tackles, TFL & 3rd-career INT last week. Has PD in 5 of 6 games in 2025 & leads all LBs with 6 PD in 2025. • LB AKEEM DAVIS-GAITHER has 5+ tackles in 4 of his past 5. • LB BARON BROWNING had 2nd sack of season last week. • DE CALAIS CAMPBELL had 3 sacks & 4 TFL in 3 home games this season. • S BUDDA BAKER is 1 of 3 NFC DBs (Kam Curl & Tykee Smith) with 5+ tackles in 6 games this season. Has 5+ tackles in 24 straight games, longest active streak by DB. Aims for his 4th in row vs. GB with 5+ tackles. • S JALEN THOMPSON has 6+ tackles in 5 of 6 games in 2025. • CB MAX MELTON aims for his 3rd in row with PD.

Game Odds

Green Bay Packers          – 7

Arizona Cardinals            44.5

Odds Courtesy of Sports Odd Direct as of Saturday, October 18, 2025