Venue & Game Details
Location: Hard Rock Stadium, Miami Gardens, FL
Kickoff: Friday, October 17, 2025 – 7:00 p.m. ET
Broadcast: ESPN
Weather: Forecast calls for warm, humid conditions in the mid-70s with light winds
Team Recent Form
Miami Hurricanes: Coming off a 28-22 win over Florida State. Miami has beaten Notre Dame, Florida, and Florida State already this season, cementing its status as a playoff contender.
Louisville Cardinals: Suffered their first loss last week, 30-27 vs. Virginia, after opening 4-0 with wins over Pitt, James Madison, and Bowling Green.
Recent Form (last 3 games):
Miami: W vs. Florida State (28-22), W vs. Florida (26-7), W vs. USF (49-12)
Louisville: L vs. Virginia (30-27), W vs. Pitt (34-27), W vs. Bowling Green (40-17)
Injury Report
Miami: No major injuries reported; QB Carson Beck and RB Mark Fletcher are fully healthy.
Louisville: No key absences; QB Miller Moss expected to start after minor ankle soreness.
Key Player Matchups
Quarterbacks:
Carson Beck (Miami) – 1,213 yards, 11 TDs, 3 INTs, 72.9% completion.
Miller Moss (Louisville) – 1,358 yards, 7 TDs, 4 INTs, 67% completion.
Running Backs:
Mark Fletcher (Miami) – 428 yards, 5 TDs.
Isaac Brown (Louisville) – 334 yards, 3 TDs.
Receivers:
Malachi Toney (Miami) – 375 yards, 3 TDs.
Chris Bell (Louisville) – 502 yards, 4 TDs.
Key Note: Miami boasts a +6 turnover margin (8th nationally), while Louisville is one of the most penalized teams in the FBS (72.4 penalty yards per game, 122nd).
Series History
Miami leads the all-time series 12-4-1.
Last meeting: Miami won 52-45 in October 2024.
Miami has covered the spread in 3 of the last 4 matchups.
Betting Trends
Miami is 4-1 ATS this season.
Louisville is 1-4 ATS this season.
The Under has hit in 3 of Miami’s last 4 games.
Louisville games have gone Over in 3 of 5 contests.
Score Projection: Miami 34 – Louisville 17
Game Odds
Louisville Cardinals 51.5
Miami Hurricanes – 13.5
Odds Courtesy of Sports Odd Direct as of Thursday, October 16, 2025
