FBS-CFB Game Preview: #9 Illinois Fighting Illini (3-0) vs. #22 Indiana Hoosiers (3-0)

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Kickoff: 7:30 PM ET
Venue: Memorial Stadium, Bloomington, Indiana
Broadcast: NBC / Peacock

Weather Forecast (Bloomington, IN)

Temperature: ~71°F (22°C) at kickoff

Conditions: Partly cloudy, light winds (5–7 mph)

Impact: Excellent football weather; no disruptions expected for passing or kicking.

Injury Report

Illinois Fighting Illini (Big Ten):

QB Luke Altmyer (196 yards, 2 TD vs. Western Michigan) healthy and efficient.

RB Kaden Feagin (100 yards, 1 TD last week) available.

WR Hank Beatty (6 catches, 53 yards, 1 TD vs. WMU) active.

No major defensive absences reported.

Indiana Hoosiers (Big Ten):

QB Fernando Mendoza (270 yards, 5 TD, 0 INT vs. Indiana State) healthy and red-hot.

RB Khobie Martin (109 yards, 2 TD vs. Indiana State) available.

WR Omar Cooper Jr. (10 catches, 207 yards, 4 TDs last week) active.

RB Lee Beebe Jr. out for the season (knee), forcing a backfield shuffle.

🔑 Key Player Matchups

QB Luke Altmyer (Illinois) vs. Indiana Secondary

Altmyer has yet to turn the ball over this season; Indiana must pressure him into mistakes.

RB Kaden Feagin (Illinois) vs. Indiana Front Seven

Feagin’s power running is crucial to Illinois’ ball-control strategy.

QB Fernando Mendoza (Indiana) vs. Illinois Pass Rush

Mendoza is completing 95% of passes in his last outing; Illinois’ defensive line must disrupt his rhythm.

WR Omar Cooper Jr. (Indiana) vs. Illinois Corners

Cooper’s 4-TD performance last week makes him the top threat Illinois must contain.

Recent Team Form

Illinois Fighting Illini (3–0, ranked #9)

8/30/25: W 38–0 vs. Western Michigan

9/6/25: W 31–14 vs. Duke

9/13/25: W 27–10 vs. Toledo

Trend: Balanced, efficient offense with a defense that has yet to allow more than 14 points.

Indiana Hoosiers (3–0, ranked #22)

8/30/25: W 34–14 vs. Temple

9/6/25: W 31–20 vs. Ohio

9/13/25: W 73–0 vs. Indiana State

Trend: Offense explosive (averaging 46 PPG), defense opportunistic, but untested against elite competition.

Series History

Last 3 meetings:

2024: Illinois 48, Indiana 45 (OT) – Champaign

2022: Indiana 23, Illinois 20 – Bloomington

2017: Indiana 24, Illinois 14 – Champaign

Overall: Indiana leads the modern series narrowly, but Illinois has momentum after last year’s OT thriller.

Betting Trends

Illinois:

3–0 ATS in 2025.

Unders hit in 2 of 3 games.

5–2 ATS in last 7 Big Ten games.

Indiana:

2–1 ATS in 2025.

Overs hit in 2 of 3 games.

4–1 ATS in last 5 home games.

Head-to-Head:

Illinois covered in 2024’s OT win.

Indiana covered in 2022 and 2017.

Historical Betting Results

Illinois: Reliable ATS early in 2025, thriving as an underdog.

Indiana: Strong at home ATS, especially as a short favorite.

Big Ten Trends: Short home favorites (-3.5 to -4.5) often draw public support, but underdogs cover late with ball-control styles.

Game Odds

Illinois Fighting Illini                       52.5

Indiana Hoosiers                              – 4

Odds Courtesy of Sports Odd Direct as of Friday, September 19, 2025