Venue & Game Details
Kickoff: 7:00 PM ET
Venue: Farris Stadium, Danville, Kentucky
Surface: FieldTurf
Broadcast: Centre College Athletics Live Stream / Live Stats
Weather Forecast (Kickoff)
Conditions: Mostly clear skies
Temperature: ~74°F (23°C) at kickoff, dropping to ~68°F by the fourth quarter
Humidity: ~60%
Wind: Light SSE breeze at 4–6 mph
Impact: Ideal football weather — minimal wind and mild temps should favor both passing and kicking games.
Injury Report
No official injury designations have been released for either team ahead of this matchup. Both DePauw and Centre are expected to have their starting quarterbacks, primary skill players, and defensive leaders available.
Recent Form
DePauw Tigers
W 40–0 @ Rose-Hulman (Sept. 6, 2025) — Dominant defensive performance; offense scored in every quarter.
2024: 9-2 overall, NCAC champions, NCAA playoff qualifier.
Centre Colonels
W 23–15 vs. Hanover (Sept. 7, 2025) — Balanced attack; defense forced two turnovers.
2024: 7-3 overall, 5-2 SAA.
Series History
Last 3 Meetings:
Sept. 14, 2024 — DePauw 38, Centre 14 (in Greencastle)
Sept. 16, 2023 — DePauw 31, Centre 13 (in Danville)
Sept. 17, 2022 — DePauw 35, Centre 21 (in Greencastle)
Trend: DePauw has won the last three meetings by an average margin of 18 points.
Key Player Matchups
DePauw QB vs. Centre Secondary — Tigers’ passing game will look to exploit a Colonels defense that allowed over 200 passing yards in Week 1.
Centre QB vs. DePauw Pass Rush — Colonels’ signal-caller must get the ball out quickly against a DePauw front that recorded multiple sacks vs. Rose-Hulman.
DePauw RB1 vs. Centre Front Seven — Establishing the run could open up play-action opportunities for the Tigers.
Centre WR1 vs. DePauw CB1 — A potential big-play battle; Centre will need chunk gains to keep pace.
Special Teams — Field position could be pivotal; DePauw’s kicker is reliable from 40+, while Centre’s return units are dangerous.
Betting Trends & Angles
DePauw: 9-1 SU in last 10 games; 8-2 ATS (unofficial DIII tracking).
Centre: 6-4 SU in last 10 games; 5-5 ATS.
Totals: Under has hit in 3 of last 4 DePauw games; Over in 3 of last 5 Centre games.
Situational: Centre home opener; DePauw on the road for second straight week.
Game Odds
DePauw Tigers – 7.5
Centre Colonels 49.5
Odds Courtesy of Sports Odd Direct as of Friday, September 12, 2025
