Venue & Kickoff
Location: Ross–Ade Stadium, West Lafayette, Indiana
Date: Saturday, September 6, 2025
Time: 7:30 PM ET
Broadcast: Big Ten Network
Capacity: 57,236
Weather Forecast
Conditions: Clear skies, mild evening
Temperature: ~64°F at kickoff
Wind: NW at 3–13 mph, gusts up to 20 mph
Precipitation: 0%
Impact: Minimal; light wind could slightly affect deep passing and kicking
Injury Report
Purdue
WR De’Nylon Morrissette – Out (did not play in opener)
WR Jalil Hall – Out (significant injury in Week 1)
LB Winston Berglund – Questionable (left Week 1 game; returning from prior injury)
Southern Illinois
No major injuries reported after Week 1 win over Thomas More
Team Records & Recent Form
Purdue: QB Ryan Browne led the Big Ten in passing after Week 1 (311 yds, 2 TD); defense pitched a shutout, allowing just 217 total yds.
Southern Illinois: QB DJ Williams threw for 227 yds, 3 TD, 0 INT; defense allowed only 191 total yds.
Key Player Matchups
QB Ryan Browne (PUR) vs. SIU Secondary
Browne: 18/26, 311 yds, 2 TD, 0 INT; 1 rush TD
SIU allowed 131 pass yds in opener
RB Devin Mockobee (PUR) vs. LB Makel Calhoun (SIU)
Mockobee: 14 carries, 59 yds, 1 TD; 2 rec, 45 yds
Calhoun: Defensive leader, key in run fits
WR Arhmad Branch (PUR) vs. CB PJ Jules (SIU)
Branch: 3 rec, 101 yds, 1 TD
Jules: Veteran DB with range
QB DJ Williams (SIU) vs. PUR Pass Rush
Williams: 17/25, 227 yds, 3 TD; 18 rush yds, 1 TD
Purdue defense: 9 sacks in opener
WR Vinson Davis (SIU) vs. CB Tahj Ra-El (PUR)
Davis: 5 rec, 89 yds
Ra-El: 7 tackles in Purdue debut
Series History
All-Time: Purdue leads 1–0
Last Meeting: Purdue 35–13 (Sept. 20, 2014, West Lafayette)
Betting Trends
Purdue: 4–1 ATS in last 5 home games vs. non-FBS opponents
SIU: 2 FBS wins in last 3 seasons (incl. 2022 vs. Northwestern)
Both teams 1–0 ATS in 2025; both went UNDER in Week 1
Purdue has lost 6 of last 7 games in Indiana overall, but covered 4 of last 5 vs. non-FBS
Game Odds
Southern Illinois Salukis 51.5
Purdue Boilermakers – 19.5
Odds Courtesy of Sports Odd Direct as of Friday, September 5, 2025
