MLB Game Preview: Milwaukee Brewers (86-55) vs. Pittsburgh Pirates (64-77)

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Pittsburgh Pirates logo

Venue & First Pitch

  • Location: PNC Park, Pittsburgh, Pennsylvania
  • Date: Friday, September 5, 2025
  • Time: 6:40 PM ET
  • Broadcast: Apple TV+ (exclusive), Brewers Radio Network, 93.7 The Fan (PIT)
  • Capacity: 38,362

Weather Forecast (Pittsburgh, PA – First Pitch)

  • Conditions: Mostly clear, mild
  • Temperature: ~74°F (23°C)
  • Wind: WSW at 4–6 mph
  • Precipitation: <5%
  • Impact: Minimal — favorable for hitters with light breeze toward left-center

Injury Report

Brewers

  • Christian Yelich (back) – Day-to-day
  • Rhys Hoskins (thumb) – 10‑day IL
  • Trevor Megill (flexor strain), D.L. Hall (oblique), Garrett Mitchell (oblique) – IL
  • Jordan Montgomery (elbow), Shelby Miller (elbow) – 60‑day IL

Pirates

  • Ronny Simon (shoulder), Jack Suwinski (groin) – 10‑day IL
  • Endy Rodriguez (elbow), Enmanuel Valdez (shoulder), Justin Lawrence (elbow), Jared Jones (elbow) – 60‑day IL

Recent Form

Brewers (Last 10): 5‑5, .279 AVG, 4.45 ERA, +3 run diff

  • Quinn Priester: 11‑2, 3.28 ERA; team has won his last 16 starts

Pirates (Last 10): 7‑3, .244 AVG, 3.10 ERA, +15 run diff

  • Riding 3‑game win streak (sweep of Dodgers) and 7‑game home win streak

Probable Pitchers

  • MIL: RHP Quinn Priester – 11‑2, 3.28 ERA, 1.24 WHIP, 107 K
    • Faced PIT May 24: 6 IP, 1 ER, 7 K (ND)
  • PIT: RHP Johan Oviedo – 2‑0, 3.60 ERA, 1.20 WHIP, 20 K in 15 IP
  • Last faced MIL Aug 6, 2023: 7 IP, 0 ER, 7 K

Key Player Matchups

  • William Contreras (MIL) vs. PIT Pitching
    • .261 AVG, 17 HR, 69 RBI; key middle-order bat
  • Bryan Reynolds (PIT) vs. Priester
    • 9-for-33 last 10 games, 3 doubles, 2 HR
  • Caleb Durbin (MIL) – 15-for-39 last 10 games, 4 doubles, 3 HR
  • Andrew McCutchen (PIT) – Veteran DH with 13 HR, 21 doubles

Series History

  • All-Time: Brewers lead 255‑196
  • 2025: Brewers 7‑3 vs. Pirates; PIT has won 2 of last 3 at PNC Park

Betting Trends

  • Brewers: 60‑11 when outhitting opponents; OVER in 4 of last 6 vs. PIT
  • Pirates: 34‑8 when scoring 5+ runs; 42‑30 at home (5th best in NL)
  • Head-to-Head: Brewers have scored 50 runs in last 6 meetings

Game Odds

Milwaukee Brewers       – 156

Pittsburgh Pirates            8.5

Odds Courtesy of Sports Odd Direct as of Thursday, September 4, 2025