MLB Game Preview: San Diego Padres (75-58) vs. Seattle Mariners (71-62)

By
MLB Editor
-
0
43
Seattle Mariners

Game Details

First pitch is scheduled for 4:10 p.m. ET, with live coverage on MLB Network and Mariners.TV.

Pitching Matchup

Seattle turns to right-hander Bryan Woo, who owns an 11-7 record with a 2.94 ERA, a 0.94 WHIP and 160 strikeouts over 159⅔ innings. Opponents are batting just .205 against him this season, and he’s sporting a streak of quality starts that includes seven of his last eight outings.

San Diego counters with veteran Yu Darvish, who is 3-3 with a 5.36 ERA and 39 strikeouts in 43.2 innings this year. The 38-year-old brings playoff pedigree and has amassed 2,046 career strikeouts, though his 2025 results have been marked by occasional inconsistency.

Team Overviews

  • San Diego Padres: 75-58 overall, 31-36 on the road; batting .251/.321/.385 with 115 home runs and 554 runs scored this season.
  • Seattle Mariners: 71-62 overall, 40-26 at home; batting .242/.318/.411 with 188 home runs and 606 runs scored, ranking among the AL’s top power clubs.

Key Storylines

Seattle holds a 2-1 edge in the season series after a 9-6 win on Monday, looking to claim Vedder Cup bragging rights in this celebrated interleague rivalry. The Mariners have also won nine of their last ten home games following a loss, while the Padres continue to struggle away from Petco Park with a 31-36 road mark this year.

Players to Watch

  • Bryan Woo (SEA): Emerging ace with an 11-7 mark, 2.94 ERA and .205 opponents’ batting average.
  • Yu Darvish (SD): Veteran southpaw at 3-3 with a 5.36 ERA, carrying 2,046 career punch-outs.
  • Cal Raleigh (SEA): Club leader with 50 home runs and 107 RBI, pacing MLB in long balls and ranking second in RBIs.
  • Manny Machado (SD): .290 hitter with team-best 149 hits, 78 RBI and 21 homers, anchoring San Diego’s middle order.

Betting Outlook

Seattle games have gone over this mark in 70 of 132 contests, and San Diego has posted a 31-30 record as underdogs this season.

With home-field advantage, power hitting and Woo’s steady command, the Mariners should edge the Padres in a tight affair.

SEO-Friendly Keywords

Game Odds

San Diego Padres             8

Seattle Mariners              – 114

Odds Courtesy of Sports Odds Direct as of Tuesday, August 26, 2025