MLB Game Preview: Boston Red Sox (71-60) vs. Baltimore Orioles (60-70)

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Baltimore Orioles logo

Game Details

Time: 6:35 PM ET
Venue: Oriole Park at Camden Yards, Baltimore, MD

Season Series

Baltimore holds a narrow 5–4 advantage in the 2025 regular-season matchup series between these AL East rivals.

Probable Pitchers

TeamPitcherSeason Stats
Red SoxBrennan Bernardino4–2, 2.93 ERA
OriolesTomoyuki Sugano10–5, 3.97 ERA, 1.27 WHIP, 85 K

Bernardino will open for Boston after a scoreless relief outing against New York over the weekend. Sugano, after a rocky midseason, has rebounded with three consecutive starts allowing one earned run or fewer.

Key Players to Watch

  • Boston Red Sox
    • Ceddanne Rafaela: 27 doubles, 3 triples, 14 HR, 53 RBI
    • Trevor Story: .260 AVG, 82 RBI, 52nd in MLB home runs
    • Jarren Duran: .334 OBP, .442 SLG, team-leading 131 hits
  • Baltimore Orioles
  • Gunnar Henderson: .283 AVG, 16 HR, 59 RBI
  • Ryan Mountcastle: 15 hits in last 10 games, including 1 HR, 7 RBI
  • Jackson Holliday: .246 AVG, 15 HR, 37 walks

Statistical Matchup

StatisticRed SoxOrioles
Win Probability (implied, Moneyline)54.5 %49.5 %
Red Sox as Favorites (this season)45–32 (58.4 %)
Orioles as Underdogs (this season)32–36 in 68 (47.1 %)
Team Batting Average.253 (4th MLB).236 (12th AL)
Team Slugging Percentage.425 (7th MLB).398 (14th AL)
  • Boston’s offense ranks fourth in MLB in batting average and runs scored, with a .425 slugging percentage that ranks seventh.
  • Baltimore is 32–36 when listed as an underdog this season, with a +100 moneyline implying a 50 % win probability.
  • The game total of 9.5 runs suggests balanced pitching matchups and moderate scoring expectations.

Boston’s balanced offense and strong late-inning relief give them the edge in a tight, low-scoring battle at Camden Yards.

Game Odds

Boston Red Sox                 – 120

Baltimore Orioles            9.5

Odds Courtesy of Sports Odds Direct as of Sunday, August 24, 2025