MLB Game Preview: Kansas City Royals (49-53) vs. Chicago Cubs (60-41)

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The Kansas City Royals and Chicago Cubs clash in the rubber match of their three-game interleague series as first pitch is scheduled for 2:20 PM ET, with the Cubs looking to build on Tuesday’s 6–0 shutout win, while the Royals aim to bounce back behind ace Seth Lugo.

Matchup Overview

  • Venue: Wrigley Field, Chicago, IL
  • Date: Wednesday, July 23, 2025
  • Time: 2:20 PM ET
  • Broadcast: MARQ (Cubs), FDSKC (Royals), MLB Network
  • Streaming: MLB.TV, FuboTV (regional restrictions may apply)

Starting Pitchers

TeamPitcherRecordERAWHIPStrikeouts
CubsColin Rea (RHP)8–33.801.0970
RoyalsSeth Lugo (RHP)6–52.941.0993
  • Colin Rea has been lights-out in July, posting a 1.45 ERA across three starts and allowing just 1 ER total in that span. He’s held opponents to a .262 batting average and has five quality starts in 2025.
  • Seth Lugo has been a model of consistency, with 10 quality starts and a .221 opponent batting average. He’s struck out 11 Cubs batters in 63 ABs and has hit the Over on strikeouts in six straight starts.

Key Players to Watch

Chicago Cubs

  • Pete Crow-Armstrong: .270 AVG, 26 HR, 72 RBI – batting .308 in July; 5 straight games with Over 1.5 total bases.
  • Kyle Tucker: .276 AVG, 18 HR, 57 RBI – ranks top 30 in MLB in homers and RBI.
  • Nico Hoerner: .285 AVG – 2-for-5 with an RBI Tuesday; team leader in batting average.
  • Seiya Suzuki: 26 HR, 80 RBI – consistent power bat with .540 xSLG.

Kansas City Royals

  • Bobby Witt Jr.: .288 AVG, 14 HR, 56 RBI – hitting .351 vs. lefties; 5 hits in last 6 games.
  • Salvador Perez: 17 HR, 60 RBI – 6 HR and 8 RBI in last 10 games.
  • Maikel Garcia: .291 AVG – team leader in batting average; 26 doubles.
  • Vinnie Pasquantino: .264 AVG, 15 HR – steady middle-of-the-order bat.

Team Stats & Trends

CategoryCubsRoyals
Batting Average.256 (3rd MLB).245 (19th MLB)
Slugging Percentage.446 (2nd).378 (24th)
Home Runs150 (3rd)81 (29th)
Runs Scored533 (2nd)355 (29th)
Team ERA3.83 (6th NL)3.78 (AL Top 5)
OBP.324 (6th).299 (26th)
  • Chicago is 33–18 at home and has won 69.6% of games as favorites.
  • Kansas City is 25–27 on the road and has won 46.8% of games as underdogs.

Final Takeaway

The Royals vs. Cubs matchup features two veteran pitchers in peak form and two lineups with contrasting identities. Chicago’s power-heavy offense, led by Crow-Armstrong, Suzuki, and Tucker, faces off against Kansas City’s contact-oriented approach anchored by Witt Jr., Garcia, and Perez. With Colin Rea surging and Seth Lugo steady, expect a tight, low-scoring affair with playoff implications and strong betting value.

Game Odds

Kansas City Royals           10

Chicago Cubs                     – 147

Odds Courtesy of Sports Odd Direct as of Tuesday, July 22, 2025