MLB Game Preview: Houston Astros (58-42) vs. Arizona Diamondbacks (50-51)

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Arizona Diamondbacks logo

The Astros enter the game holding a 1–0 series lead after a 6–3 win in the opener. This matchup features a marquee pitching duel between Framber Valdez and Eduardo Rodríguez, and showcases rising stars like Brice Matthews, Corbin Carroll, and Eugenio Suárez. It’s a must-watch for MLB fans, DFS players, and sports bettors tracking the AL West and NL Wild Card races.

Matchup Overview

  • Venue: Chase Field, Phoenix, AZ
  • Date: Tuesday, July 22, 2025
  • Time: 9:40 PM ET
  • Broadcast: SCHN (Astros), DBACKS.tv
  • Streaming: MLB.TV, FuboTV (regional restrictions may apply)

Starting Pitchers

TeamPitcherRecordERAWHIPStrikeouts
AstrosFramber Valdez (LHP)10–42.751.12125
D-backsEduardo Rodríguez (LHP)3–65.941.6790
  • Valdez has been dominant, allowing 0 ER in his last start and leading Houston to 12 straight wins when he takes the mound.
  • Rodríguez has struggled, giving up 4 ER in his last outing and losing three consecutive starts.

Key Players to Watch

Houston Astros

  • Brice Matthews: Hit his first two career home runs Monday, driving in 5 RBI to lead the Astros to victory.
  • Christian Walker: .213 AVG, 10 HR, 37 RBI – returned to Chase Field after signing with Houston in the offseason.
  • Jose Altuve: .260 AVG, 13 HR, 36 RBI – veteran spark plug with 6 stolen bases.
  • Jeremy Peña: .322 AVG, 11 HR, 40 RBI – currently day-to-day with a rib injury.

Arizona Diamondbacks

  • Eugenio Suárez: NL leader with 36 HR and 85 RBI – homered again Monday.
  • Corbin Carroll: .258 AVG, 18 HR, 39 RBI – dynamic leadoff hitter with 10 stolen bases.
  • Geraldo Perdomo: .271 AVG, 43 RBI – consistent contact hitter with 59 walks.
  • Ketel Marte: .299 AVG, 12 HR, 21 RBI – returned from a brief absence and scored in Game 1.

Team Stats & Trends

CategoryAstrosD-backs
Batting Average.234 (Last 10 games).254 (Last 10 games)
Slugging Percentage.394.445
Home Runs100 (21st MLB)146 (3rd NL)
Runs Scored457 (12th MLB)432 (19th MLB)
Team ERA4.83 (Last 10)3.87 (Last 10)
WHIP1.271.57
  • Astros have been outscored by 10 runs over their last 10 games.
  • Diamondbacks have outscored opponents by 14 runs in the same span.

Game Odds

Houston Astros                                 – 126

Arizona Diamondbacks                 8.5

Odds Courtesy of Sports Odd Direct as of Monday, July 21, 2025