MLB Game Preview: Cincinnati Reds (52-49) vs. Washington Nationals (40-60)

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Washington Nationals logo

The Nationals took the opener in a high-scoring 10–8 victory, and the Reds aim to bounce back behind a promising young arm.

Matchup Overview

  • Venue: Nationals Park, Washington, D.C.
  • Date: Tuesday, July 22, 2025
  • Time: 6:45 PM ET
  • Broadcast: MASN (Nationals), Bally Sports Ohio (Reds)
  • Streaming: FuboTV, MLB.TV (regional restrictions may apply)

Starting Pitchers

TeamPitcherRecordERAWHIPK/9
RedsChase Burns (RHP)0–16.191.6314.1
NationalsBrad Lord (RHP)2–53.461.257.8
  • Chase Burns is making his fifth career start. Despite a rocky debut, he’s shown flashes of dominance, including a 10-strikeout performance in his last outing.
  • Brad Lord has quietly been one of Washington’s most reliable arms, allowing zero earned runs in his last two appearances.

Key Players to Watch

Cincinnati Reds

  • Elly De La Cruz: Batting .279 with 18 HR, 65 RBI, 26 SB, and a .843 OPS. He walked three times and scored three runs in Monday’s loss.
  • Gavin Lux: 2-for-5 with 2 RBI in Game 1; batting .265 with 39 RBI on the season.
  • Noelvi Marte: Delivered two hits and two RBI in the opener; hitting .277 with 25 RBI.

Washington Nationals

  • James Wood: Leads the team with 24 HR and 69 RBI; batting .275 with 14 stolen bases.
  • Brady House: 3-for-4 with 2 runs scored Monday; hitting .282 over his last 10 games.
  • Daylen Lile: Hit a bases-clearing triple in the first inning Monday and added a solo homer later.

Team Stats & Trends

StatRedsNationals
Batting Average.246 (16th in MLB).246 (16th)
Runs Scored464 (10th)434 (18th)
Home Runs107 (17th)98 (22nd)
Team ERA3.87 (13th)5.22 (28th)
WHIP1.24 (10th)1.41 (26th)
  • Cincinnati has allowed 3 or fewer runs in 7 of its last 9 games.
  • Washington has allowed 6+ runs in 7 of its last 8 games, despite Monday’s win.

Final Takeaway

The Reds vs. Nationals matchup on July 22, 2025, features two young pitchers with upside and two lineups capable of explosive innings. With Elly De La Cruz, James Wood, and Brady House all swinging hot bats, expect another high-scoring affair. Cincinnati’s deeper bullpen and offensive consistency give them the edge, but Washington’s recent surge makes this a compelling contest for fans and bettors alike.

Game Odds

Cincinnati Reds                                 – 136

Washington Nationals                   9

Odds Courtesy of Sports Odd Direct as of Monday, July 21, 2025