MLB Game Preview: San Francisco Giants (45-38) vs. Chicago White Sox (27-56)

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First pitch is set for 2:10 p.m. ET, with coverage on NBC Sports Bay Area, NBC Sports Chicago, and MLB.tv.

MatchupSan Francisco Giants vs Chicago White Sox
Date & TimeSunday, June 29 – 2:10 p.m. ET
VenueGuaranteed Rate Field, Chicago, IL
BroadcastNBCSBA, NBCSCH, MLB.tv

This is the series finale of a three-game interleague set. The series is tied 1–1, with both teams looking to claim the rubber match.

Team Form & Trends

San Francisco Giants (45–38, 3rd in NL West)

  • Recent Form: 4–6 in last 10 games
  • Pitching Strength: 3rd-best team ERA in MLB (3.39)
  • Offensive Leaders:
  • Heliot Ramos: .280 AVG, 13 HR, 44 RBI – team leader in all three categories
  • Rafael Devers: 17 HR, 20 doubles – power bat heating up
  • Casey Schmitt: 12-for-33 (.364) with 2 HR in last 10 games

Chicago White Sox (27–56, 5th in AL Central)

  • Recent Form: 3–7 in last 10 games
  • Home Record: 18–24 at Guaranteed Rate Field
  • Offensive Leaders:
  • Miguel Vargas: 10 HR, 34 RBI – leads team in both categories
  • Andrew Benintendi: 4 HR, 8 RBI in last 10 games
  • Lenyn Sosa: .294 AVG over last 10 games with 2 HR

Probable Starting Pitchers

San Francisco Giants: Robbie Ray (LHP)

  • Record: 7–3 ERA: 3.12 WHIP: 1.09
  • Last Start: 6.0 IP, 1 ER, 8 K vs Rockies
  • Trend: Giants are 13–3 in games started by Ray this season

Chicago White Sox: Adrian Houser (RHP)

  • Record: 2–6 ERA: 5.02 WHIP: 1.47
  • Last Start: 5.1 IP, 3 ER vs Tigers
  • Trend: 0.75 ERA in 2 starts at Guaranteed Rate Field this season

Key Matchups to Watch

  • Ramos & Devers vs Houser: Both left-handed hitters have slugging percentages over .500 against righties
  • Benintendi vs Ray: Benintendi has 4 HR in his last 10 games and could be the key to breaking through against the lefty
  • Bullpen Battle: Giants’ bullpen ERA (3.41) ranks top 5; White Sox relievers have struggled in late innings

Head-to-Head & Betting Insights

  • Season Series: Tied 1–1 entering Sunday’s finale
  • Giants are 30–24 as favorites this season
  • White Sox are 27–56 overall, including 14–41 when allowing a home run
  • Over is 4–6 in Giants’ last 10 games; Under is 7–3 in White Sox’s last 10

Game Odds

San Francisco Giants      – 160

Chicago White Sox          8.5

Odds Courtesy of Sports Odds Direct as of Saturday, June 28, 2025