MLB Game Preview: Chicago Cubs (46-32) vs. St. Louis Cardinals (43-36)

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St. Louis Cardinals logo

Game Details

  • Matchup: Chicago Cubs (46–32) vs. St. Louis Cardinals (43–36)
  • Date: Tuesday, June 24, 2025
  • First Pitch: 7:45 PM ET
  • Venue: Busch Stadium, St. Louis, MO
  • Broadcast: MARQ (Cubs), Bally Sports Midwest (Cardinals), MLB.TV

Game Context & Stakes

The Cardinals took Game 1 of the series with an 8–2 win, closing the gap in the NL Central standings. They’ve now won 7 of their last 10 games, outscoring opponents by 23 runs during that stretch.

The Cubs, despite leading the division, have cooled off—going 5–5 in their last 10 with a 5.14 team ERA. Tuesday’s game is pivotal: a Cardinals win would shrink Chicago’s lead to just 0.5 games, while a Cubs bounce-back would restore breathing room.

Probable Starting Pitchers

Chicago Cubs – Jameson Taillon (RHP)

  • Record: 7–4
  • ERA: 3.84
  • WHIP: 1.04
  • Last Start: 4.0 IP, 5 ER vs. Brewers
  • Scouting Report: Taillon has been excellent on the road, especially at Busch Stadium, where he’s 4–0 with a 2.58 ERA in six career starts. He’ll look to rebound from a rough outing and keep the Cubs in control of the division.

St. Louis Cardinals – Michael McGreevy (RHP)

  • Record: 1–1
  • ERA: 2.70
  • WHIP: 0.84
  • Last Start: 5.0 IP, 1 ER, 3 H vs. Marlins
  • Scouting Report: The rookie right-hander has impressed in limited action, mixing seven pitches to keep hitters off balance. He’s allowed just 3 earned runs in 16.2 MLB innings this season.

Players to Watch

Chicago Cubs

  • Kyle Tucker: .285 AVG, 15 HR, 46 RBI – riding a 3-game hitting streak
  • Pete Crow-Armstrong: 21 HR (6th in MLB), 5th in RBI – 3 HR in last 5 games
  • Seiya Suzuki: Team-high 64 RBI
  • Nico Hoerner: .284 AVG, 17 doubles – consistent top-of-the-order bat

St. Louis Cardinals

  • Nolan Arenado: 10 HR, 3-game hit streak – .300 AVG in last 5 games
  • Alec Burleson: 16-for-43 (.372) with 4 HR in last 10 games
  • Brendan Donovan: .308 AVG – team leader in batting average
  • Willson Contreras: 10 HR, 50 RBI – key run producer

Trends

  • Cubs are 3–7 ATS in their last 10 games
  • Cardinals are 6–4 ATS in their last 10
  • OVER has hit in 7 of last 8 Cubs–Cardinals games at Busch Stadium
  • Cubs are 34–13 when favored by –120 or more this season

How to Watch Cubs vs Cardinals – June 24, 2025

  • TV Channels: MARQ (Cubs), Bally Sports Midwest (Cardinals)
  • Streaming: MLB.TV, FuboTV
  • Radio: 670 The Score (CHI), KMOX 1120 AM (STL)

Game Odds

Chicago Cubs                     – 121

St. Louis Cardinals           9

Odds Courtesy of Sports Odds Direct as of Monday, June 23, 2025

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MLB Editor
Profile: A dedicated Major League Baseball analyst with a comprehensive understanding of the sport’s strategic, statistical, and developmental layers. This columnist delivers in‑depth coverage that blends advanced metrics, scouting insight, and historical context to illuminate the trends shaping today’s game. Background: With extensive experience following MLB at both the team and league levels, the columnist has contributed to national sports outlets, digital platforms, and radio segments focused on roster construction, player evaluation, and organizational philosophy. A background in sports journalism and analytics supports a disciplined approach to breaking down performance, interpreting data, and tracking long‑term competitive cycles. Signature Coverage Areas: Game previews and pitching‑matchup analysis Advanced statistical breakdowns and sabermetric insights Prospect evaluation, farm‑system trends, and player development Trade‑deadline movement, free‑agency analysis, and front‑office strategy Historical context and postseason features Style & Approach: The writing emphasizes clarity, accuracy, and accessibility — translating complex data and tactical nuance into insights that resonate with both traditional fans and analytically minded readers. Each column reflects a commitment to balanced reporting, thoughtful evaluation, and a deep appreciation for the evolving landscape of Major League Baseball.