MLB Game Preview: St. Louis Cardinals (12-16) vs. Cincinnati Reds (15-13)

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Cincinnati Reds logo

The St. Louis Cardinals and Cincinnati Reds are set to face off on April 28, 2025, at the Great American Ball Park in Cincinnati, Ohio. This game marks the first of a four-game series between these NL Central rivals, with both teams looking to gain an early edge in the series.

Team Overview

Cincinnati Reds

The Reds enter this matchup with a 15-13 record, showcasing solid form at home. Nick Martinez is expected to start for Cincinnati. Martinez has struggled this season, holding a 0-3 record with a 5.40 ERA across 26 2/3 innings pitched. While he has shown flashes of potential, his consistency on the mound will be critical in this game.

Offensively, the Reds have been powered by Elly De La Cruz, who leads the team with five home runs and 24 RBIs. De La Cruz is riding an 11-game hitting streak, batting .341 during this stretch. TJ Friedl and Noelvi Marte have also been key contributors, adding depth to Cincinnati’s lineup. The Reds rank 11th in MLB with 32 home runs and boast a .254 team batting average, placing them among the league’s top offenses.

St. Louis Cardinals

The Cardinals, with a 12-16 record, have struggled to find consistency this season. Andre Pallante is set to start for St. Louis. Pallante has been more reliable, holding a 2-1 record with a 4.15 ERA. His ability to navigate through Cincinnati’s potent lineup will be a key factor for the Cardinals.

Offensively, the Cardinals are led by Lars Nootbaar and Brendan Donovan, who have been consistent at the plate. The team ranks first in MLB with a .265 batting average and ninth in slugging percentage (.401). However, their pitching staff has struggled, which has been a significant factor in their slow start to the season.

Key Matchups

  • Nick Martinez vs. Andre Pallante: Both starting pitchers will play a pivotal role in setting the tone for the game.
  • Elly De La Cruz vs. Cardinals’ Pitching: De La Cruz’s hot streak makes him a key player to watch.
  • Lars Nootbaar vs. Reds’ Defense: Nootbaar’s ability to get on base and drive in runs could be a game-changer for St. Louis.

Game Dynamics

The Reds are slight favorites, with a win probability of 55.4%. Their home-field advantage and strong offensive lineup give them an edge. However, the Cardinals’ ability to hit for average and their potential for timely hitting make them a dangerous opponent.

Game Odds

St. Louis Cardinals           8.5

Cincinnati Reds                 – 122

Odds Courtesy of Sports Odds Direct as of Sunday, April 27, 2025

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