MLB Game Preview: Cleveland Guardians (10-9) vs. Pittsburgh Pirates (8-13)

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The Cleveland Guardians and Pittsburgh Pirates are set to face off in Game 2 of their three-game series at PNC Park in Pittsburgh on April 19, 2025, at 4:05 p.m. ET. The Guardians took the series opener with a 10-7 victory, powered by a strong offensive performance from Bo Naylor, who went 3-for-5 with a home run, a double, and three RBIs.

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Team Overview & Season Performance

Cleveland Guardians (10-9, No. 3 in AL Central)

  • The Guardians snapped a two-game losing streak with their win on April 18.
  • Bo Naylor led the charge offensively, delivering a two-run double and a solo home run.
  • Luis Ortiz pitched five solid innings, striking out eight batters while allowing two runs on four hits.
  • Cleveland’s offense exploded for five runs in the seventh inning, breaking the game open.

Pittsburgh Pirates (8-12, No. 4 in NL Central)

  • The Pirates have struggled recently, losing three of their last four games.
  • Bryan Reynolds went 3-for-5 with two RBIs, including a solo home run in the seventh inning.
  • Oneil Cruz hit a leadoff home run for the second consecutive game, showcasing his power.
  • Pittsburgh’s bullpen allowed five runs in the seventh, which proved costly.

Key Matchups & X-Factors

Paul Skenes vs. Guardians’ Offense

  • Skenes (2-1, 2.96 ERA) will start for the Pirates on his bobblehead day, adding extra excitement to the matchup.
  • He has been dominant, striking out 26 batters in 24⅓ innings this season.
  • If Skenes can control Cleveland’s lineup early, Pittsburgh will have a strong chance to bounce back.

Ben Lively vs. Pirates’ Power Hitters

  • Lively (1-2, 6.06 ERA) will take the mound for Cleveland, looking to build off his last outing.
  • Pittsburgh’s lineup has shown flashes of power, hitting three home runs in their last game.
  • If Lively struggles, the Pirates could capitalize with another offensive surge.

Bullpen Battle

  • Cleveland’s bullpen held strong in the ninth inning, with Emmanuel Clase securing his third save of the season.
  • Pittsburgh’s relievers need to step up after allowing five runs in the seventh inning.
  • If the Guardians’ bullpen remains solid, they could secure another win.

Game Odds

Cleveland Guardians                      8

Pittsburgh Pirates                            – 175

Odds Courtesy of Sports Odds Direct as of Friday, April 18, 2025