NFL Preview: New England Patriots (1-2) vs San Francisco 49ers (1-2)

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San Francisco 49ers logo

TV: FOX (4:05 PM ET): Joe Davis, Greg Olsen, Pam Oliver (field reporter)

All-Time Series History Regular Season: SF leads series, 9-5 (Away team won past 4) Postseason: —

The Last Time… Regular Season: 10/25/20: SF 33 at NE 6 Postseason: —

HEAD COACHES

Jerod Mayo vs. Opp. (incl. postseason): — Reg. Season: 1-2 (.333) Postseason: —

Kyle Shanahan vs. Opp. (incl. postseason): 1-0 Reg. Season: 65-53 (.551) Postseason: 6-3 (.667)

PATRIOTS NOTES

• QB JACOBY BRISSETT completed 12 of 18 atts. (66.7 pct.) with 0 INTs last week, 3rd-straight start with 0 INTs. Completed 22 of 34 atts. (64.7 pct.) for 314 yards & had rush TD in only career start vs. SF (10/8/17 w/ Ind.). • QB DRAKE MAYE (rookie) made NFL debut in Week 3, completing 4 of 8 atts. • RB RHAMONDRE STEVENSON has 90+ scrimmage yards & rush TD in 2 of 3 games this season. Has 50+ scrimmage yards in 4 of his past 5 on road. Aims for 4th in row vs. NFC with 90+ scrimmage yards & rush TD. • RB ANTONIO GIBSON led team with 29 rush yards last week. • TE HUNTER HENRY has 179 rec. yards (89.5 per game) in 2 career games vs. NFC West. • WR DEMARIO DOUGLAS had 7 catches for team-high 69 yards in Week 3. • DE KEION WHITE aims for 3rd in row with 6+ tackles. Has 1.5+ sacks in 2 of 3 games this season & ranks tied-3rd in NFL with 4 sacks in 2024. Aims for his 3rd in row vs. NFC with sack. • DE DEATRICH WISE JR. had 1st sack of season last week. Has sack in 2 of his past 3 on road. • LB JOSHUA UCHE had 1st sack of season in Week 3. Has TFL in 3 of his past 4 on road. • LB ANFERNEE JENNINGS had 6 tackles & 2 TFL last week. Aims for his 3rd in row with 6+ tackles. Had 5 tackles in last meeting. • LB RAEKWON MCMILLAN led team with 10 tackles in Week 3, his 3rd-career game with 10+ tackles. Aims for 3rd in row with 6+ tackles. • LB JAHLANI TAVAI had 9 tackles & TFL last week. • CB JONATHAN JONES had 7 tackles, PD & FF in Week 3, his 8th-career FF. Aims for 5th in row on road with PD. Had 7 tackles in last meeting. • S KYLE DUGGER has 5+ tackles in 8 of his past 9. Has FF & PD in 2 of his past 3 on road.

49ERS NOTES

• QB BROCK PURDY had 333 yards (292 pass, 41 rush) & 3 TD passes vs. 0 INTs for 137.1 rating in Week 3, his 7th-career game with 3+ TD passes. Has 9 career games with 130+ rating, most by QB in 1st 3 seasons in NFL history. Has 110+ rating in 15 of his 1st 24 career starts, 1 of 2 (Patrick Mahomes) with 15+ such games in 1st 25 career starts all-time. • RB JORDAN MASON had 88 scrimmage yards (77 rush, 11 rec.) in Week 3. Ranks 2nd in NFL with 324 rush yards & is 1 of 3 (Saquon Barkley & Alvin Kamara) with 75+ rush yards in each of 1st 3 weeks. • WR JAUAN JENNINGS set career highs in receptions (11), rec. yards (175) & rec. TDs (3) in Week 3 & became 2nd player in franchise history (HOFer Jerry Rice) with 10+ catches, 150+ rec. yards & 3+ rec. TDs in single game. • WR BRANDON AIYUK had season highs in catches (5) & rec. yards (48) in Week 3. Had 6 catches for 115 yards in last meeting. Has 5+ catches & 100+ rec. yards in 4 of his past 6 home games. • TE GEORGE KITTLE has 65+ rec. yards in 5 of his past 6 at home. Had 5 catches for 55 yards in last meeting. • LB FRED WARNER had 49th-career PD last week, most among LBs since entering NFL in 2018. Had 7 tackles & INT in last meeting. • DL NICK BOSA had TFL in Week 3, his 75th-career TFL. Aims for his 3rd in row with TFL. • DL MALIEK COLLINS had 1st sack of season last week. • CB CHARVARIUS WARD led team with 9 tackles in Week 3. Aims for his 4th in row with PD. • CB DEOMMODORE LENOIR had 9th-career TFL last week. • S JI’AYIR BROWN had 2 PD last week, his 2nd-career game with 2+ PD. • S TALANOA HUFANGA had 7 tackles in season debut in Week 3.