CBS: Ian Eagle, Ross Tucker, Evan Washburn (field reporter)
Kickoff is scheduled for 1:00 PM ET
Highmark Stadium
Referee: Bill Vinovich
Regular Season: NE leads series, 79-51-1 (NE won 2 of past 3)
Last reg. season meeting: 12/14/25: BUF 35 at NE 31
Mike Vrabel (NE) vs. Opp. (incl. postseason): 3-4 Reg. Season: 69-50 (.580)
Joe Brady (BUF) vs. Opp. (incl. postseason): 0-0 Reg. Season: 3-0 (1.000)
New England Last Game: L, 35-6 at JAX (Week 3)
Buffalo Last Game: W, 24-16 vs. LAC (Week 3)
PATRIOTS NOTES
• QB DRAKE MAYE passed for 199 yards in Week 3. Has 60+ comp. pct. & TD pass in 4 of his past 5 on road. Completed 14 of 23 atts. (60.9 pct.) for 155 yards & had 2 rush TDs in last meeting. • RB RHAMONDRE STEVENSON had 38 scrimmage yards (22 rush, 16 rec.) last week. Has 70+ scrimmage yards in 4 of his past 5 on road, incl. playoffs. Had 77 scrimmage yards (50 rush, 27 rec.) in last meeting. • RB TREVEYON HENDERSON has 50+ rush yards & rush TD in 2 of his past 3. Had 161 scrimmage yards (148 rush, 13 rec.) & 2 rush TDs in last meeting. • WR MACK HOLLINS led team in receptions (6) & rec. yards (87) in Week 3. Played for Buf. in 2024, totaling 31 receptions for 378 yards & 5 TDs. Has 50+ scrimmage yards in 5 of his past 6 on road. Had 41 rec. yards in last meeting. • WR ROMEO DOUBS had 49 rec. yards last week. Had 62 rec. yards & rec. TD in his only career game vs. Buf. (10/30/22 w/ GB). • LB ROBERT SPILLANE had 7 tackles in Week 3. Aims for his 4th in row with 6+ tackles. Had 9 tackles & FF in his last game vs. Buf. (10/5/25). • LB GABE JACAS (rookie) had 5 tackles & 0.5 sack last week. Has 0.5+ sacks in 2 of his past 3. • LB ELIJAH PONDER had 0.5 sack in Week 3. Has 0.5+ sack in 3 of his past 4. • LB ERICK HUNTER (rookie) had 1st-career TFL last week. • CB CHRISTIAN GONZALEZ had PD in Week 3. Aims for his 8th in row, incl. playoffs, with PD & 3rd in row vs. Buf. with 5+ tackles & PD. Had 5 tackles & PD in last meeting. • CB CARLTON DAVIS led team with 8 tackles & had TFL & PD last week. Has 6+ tackles in 3 of his past 4, incl. playoffs. Had 4 tackles, TFL & PD in last meeting. • CB MARCUS JONES had 4 tackles, 3 PD & INT in Week 3. Had 10 tackles in last meeting. • S KEVIN BYARD had 5 tackles last week. Has 5+ tackles in 5 of his past 6, incl. playoffs. Had 13 tackles in his last game vs. Buf. (11/26/23 w/ Phi.).
BILLS NOTES
• QB JOSH ALLEN completed 16 of 26 atts. (61.5 pct.) for 204 yards & had 2 rush TDs in Week 3, becoming 1st QB all-time with 2+ rush TDs in 3 consecutive games. Became 4th player ever with 6+ rush TDs in 9 consecutive seasons (HOFers Marshall Faulk – 10, LaDainian Tomlinson – 10 & Jim Brown – 9). Needs win to tie HOFer Peyton Manning (92) for 3rd-most reg. season wins by QB all-time & become 4th QB ever with 100+ wins, incl. playoffs, in 1st 9 seasons. Completed 19 of 28 atts. (67.9 pct.) for 193 yards & 3 TDs with 123.1 rating. • RB JAMES COOK led team with 154 rush yards & had rush TD last week. Aims for his 3rd in row with 135+ rush yards & rush TD. Had 111 scrimmage yards (107 rush, 4 rec.) & 3 TDs (2 rush, 1 rec.) in last meeting. • RB TY JOHNSON had 50 rec. yards in Week 3. Aims for his 3rd in row with 50+ scrimmage yards. • WR DJ MOORE had 6 catches for 67 yards last week. Has 5+ catches & 65+ rec. yards in 2 of his past 3. • TE DAWSON KNOX had 2 rec. TDs in last meeting. • LB GREG ROUSSEAU had 8 tackles, 4 TFL & 2 sacks in Week 3, becoming 3rd player since 1982 with 2+ sacks in each of team’s 1st 3 games of season. Aims for his 7th in row with 0.5+ sacks. Had 3 tackles & sack in last meeting. • LB DORIAN WILLIAMS led team with 9 tackles last week. Has 6+ tackles & TFL in 3 of his past 4. • DL LANDON JACKSON had 4 tackles & 1st-career PD in Week 3. • S C.J. GARDNER-JOHNSON had 5 tackles, 2 PD & INT last week. Has 5+ tackles in 4 of his past 5. Had 5 tackles, 2 TFL, sack & PD in his last game vs. NE (9/26/21 w/ NO). • CB DEE ALFORD had 5 tackles & PD in Week 3. Had 4 tackles & PD in his only career game vs. NE (11/2/25 w/ Atl.). • CB DAVISON IGBINOSUN (rookie) had career-high 5 tackles & PD last week. • CB MAXWELL HAIRSTON had PD in Week 3. Had 6 tackles in last meeting
Game Odds
New England Patriots 49
Buffalo Bills – 6.5
Odds Courtesy of Sports Odd Direct as of Saturday, October 3, 2026
