Regular Season: SEA leads series, 31-22-1 (SEA won past 9)
Last meeting: 11/9/25: ARI 22 at SEA 44
Mike Macdonald (SEA) vs. Opp. (incl. postseason): 4-0 Reg. Season: 24-10 (.706)
Mike LaFleur (ARI) vs. Opp. (incl. postseason): 0-0 Reg. Season: 1-0 (1.000)
SEAHAWKS NOTES
• SEAHAWKS led NFL with 3 INTs in Week 1. • QB SAM DARNOLD ranked 5th with 4,048 pass yards in 2025. Became 4th QB ever to win Super Bowl in 1st season with team, joining Tom Brady, Trent Dilfer & Matthew Stafford. Passed for 242 yards & TD for 111.4 rating in last road meeting. Aims for 4th in row vs. Ari. with TD pass. • QB DREW LOCK passed for 187 yards & TD for 113.3 rating in Week 1. Has 6,556 pass yards & 35 TD passes in 42 career games. • RB JADARIAN PRICE rushed for 52 yards in Week 1, 2nd-most among rookies. • WR JAXON SMITH-NJIGBA had 8 catches for 122 yards & TD in Week 1. Has 75+ rec. yards in 8 of his last 9 on road. Has TD in 3 of his last 4 vs. Ari. & aims for 5th in row vs. Ari. with 75+ rec. yards. • WR COOPER KUPP aims for 8,500 career rec. yards (8,404) & 60 career TD catches (59). Had 74 rec. yards in last meeting. • TE AJ BARNER had career-high 52 receptions for 519 yards & 6 TDs in 2025. Had TD catch in last road meeting. • DT LEONARD WILLIAMS had sack in Week 1. Has sack & PD in 3 of his last 4 vs. Ari. • DT BYRON MURPHY II had TFL in Week. Had career-high 7 sacks last season. • LB DERRICK HALL had sack in Week 1. • LB DRAKE THOMAS had 9 tackles & sack in Week 1. • LB DEMARCUS LAWRENCE had 2 FR-TDs in last meeting. • LB ERNEST JONES IV led team with 13 tackles in Week 1, tied-3rd most in NFL in Week 1. Aims for 3rd in row vs. Ari. with INT. • CB JOSH JOBE had 6 tackles & INT in Week 1. Aims for 4th in row vs. Ari. with PD. • CB NEHEMIAH PRITCHETT had 6 tackles, 2 PD & INT last week. • CB DEVON WITHERSPOON has 5+ tackles in 4 of his last 5 vs. Ari. • S JULIAN LOVE had 6 tackles, 2 TFL & INT in Week 1. Has PD in 4 of his last 5 vs. Ari. • S NICK EMMANWORI had 9 tackles & 4 PD in last meeting.
CARDINALS NOTES
• QB JACOBY BRISSETT passed for 277 yards & TD for 103.1 rating in Week 1. Passed for 258 yards & 2 TD in last meeting. Aims for 4th in row vs. Sea. with TD pass. • RB JEREMIYAH LOVE had rush TD in NFL debut last week, 1 of 2 rookies with rush TD in Week 1. • RB TYLER ALLGEIER led team with 61 rush yards in Week 1. Recorded careerhigh 8 rush TDs in 2025 w/ Atl. • WR MARVIN HARRISON JR. ranks 5th among qualified WRs (100+ receptions) with 14.7 yards per reception since entering the NFL in 2024. Aims for 3rd in row vs. Sea. with TD catch. • WR MICHAEL WILSON had 5 receptions for 56 yards in Week 1. Recorded career-high 78 receptions for 1,006 rec. yards & 7 TD catches in 2025. • WR KENDRICK BOURNE had 8 catches for 75 yards last week. • TE TREY MCBRIDE led team with 9 receptions for 95 yards & TD in Week 1, his 38th career game with 5+ receptions, tied with HOFers Antonio Gates & Kellen Winslow Sr. for 2nd-most such games by TE in 1st 5 seasons in NFL history. Had 9 catches for 127 yards & TD in last meeting. • OLB JOSH SWEAT aims for 3rd in row vs. Sea. with sack. Had FF & FR in last meeting. • ILB MACK WILSON had 6 tackles & PD in Week 1. • ILB JACK GIBBENS led team with 7 tackles & had 0.5 sacks last week. • CB DENZEL BURKE co-led all rookies with 11 PD last season & had 3 INTs, 2ndmost among rookies. • S BUDDA BAKER had 5 tackles & 0.5 sacks in Week 1. Leads all safeties with 1,008 tackles since entering NFL in 2017, 1 of 2 active safeties (Harrison Smith) since 2000 with 1,000+ career tackles. • S ANDREW WINGARD had 2 TFL, INT & FF in Week 1.
Game Odds
Seattle Seahawks – 4
Arizona Cardinals 41
Odds Courtesy of Sports Odd Direct as of Saturday, September 19, 2026
