Venue: PNC Park, Pittsburgh, Pennsylvania.
First pitch: 6:40 p.m. ET.
Probable starters: RHP Logan Henderson (Brewers, 10-3, 2.34 ERA, 0.78 WHIP, 99 K in 88.1 IP) vs. RHP Jared Jones (Pirates, 4-6, 4.10 ERA, 1.17 WHIP, 100 K in 85.2 IP).
Weather Forecast
Mostly sunny to partly cloudy with a high near 88°F. Chance of showers and thunderstorms in the afternoon/evening (30–50%). Southwest winds around 5 mph. Warm and humid conditions possible; monitor for any delays at the outdoor park.
Injury Reports
Brewers: Cooper Pratt (day-to-day, illness; probable), Bryse Wilson (15-day IL, back), Grant Anderson (15-day IL, biceps), Brandon Woodruff (60-day IL, shoulder), Rob Zastryzny (60-day IL), and longer-term absences including Angel Zerpa and others.
Pirates: Kirby Yates (15-day IL, shoulder), Braxton Ashcraft (15-day IL, arm), Isaac Mattson (15-day IL, hip), Esmerlyn Valdez (10-day IL, hamstring), Mitch Keller (60-day IL, arm), and Endy Rodríguez (60-day IL).
Current active groups feature Brewers stars such as Jackson Chourio, Brice Turang, William Contreras, Christian Yelich, Jake Bauers, Joey Ortiz, and Luis Lara. Pirates rely on Brandon Lowe, Bryan Reynolds, Oneil Cruz, Nick Gonzales, Konnor Griffin, Rafael Flores Jr., and available depth.
Recent Team Forms
Brewers: 94-57 (first in NL Central). Won 5-1 on Tuesday (Misiorowski dominant) and clinched their fourth straight division title after the Cubs lost. Last 10: 7-3. Road: 42-31. Strong offense (.259 AVG) and excellent pitching (team ERA ~3.56). Momentum is high post-clinch.
Pirates: 75-76 (third in NL Central). Lost 1-5 on Tuesday (third loss in four games). Last 10: 6-4. Home: 38-35. Competitive but inconsistent; power present (171 HR) with a team ERA ~4.18. Playing out the season.
Series History
Pirates lead the 2026 season series 6-5 entering Wednesday (or close; Brewers took the most recent game). Competitive NL Central matchups throughout the year. The current series is underway with Milwaukee taking Game 1.
Key Player vs. Player Matchups / Pitching Edge
Clear edge to Henderson, who has been outstanding with elite control (tiny WHIP) and a strong strikeout rate in limited but highly effective work. Jones has solid strikeout ability but a higher ERA and more walks.
Key hitters: Chourio, Turang, Contreras, Yelich, and Bauers vs. Jones; Lowe, Reynolds, Cruz, Gonzales, and Flores vs. Henderson. PNC Park is generally pitcher-friendly, which could favor Henderson’s profile.
Betting Trends
Brewers favored on the road as the superior team with division-clinching momentum.
Recent series game stayed low-scoring.
Brewers have strong road form and pitching advantages.
Game Odds
Milwaukee Brewers – 118
Pittsburgh Pirates 7.5
Odds Courtesy of Sports Odds Direct as of Tuesday, September 15, 2026
