MLB Game Preview: Cleveland Guardians (74-72) vs. Baltimore Orioles (70-76)

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Baltimore Orioles logo

Oriole Park at Camden Yards in Baltimore, Maryland.

First pitch is scheduled for 6:35 p.m. ET.

TV options include MASN and CleGuardians.TV; streaming is available via Fubo and similar services.

Starting Pitchers

Guardians: LHP Foster Griffin (15-4, 3.26 ERA, 1.14 WHIP, 142 K in 160.1 IP). Acquired from the Nationals midseason; he is 3-1 with a 4.06 ERA in six starts for Cleveland. Road splits are strong (roughly 3.14 ERA in 14 starts). He previously faced Baltimore while with Washington (one unearned run over seven innings on June 27). Career vs. Orioles hitters in limited sample shows strong results (very low average against key bats like Alonso and Henderson).

Orioles: RHP Shane Baz (5-15, 3.91 ERA, 1.33 WHIP, 145 K in 163.1 IP). He has pitched better than his record indicates, with recent strong outings (e.g., limiting damage in recent starts, including a quality outing vs. Boston). Home ERA is solid; he has faced Cleveland before with mixed results (career vs. Guardians around a 4.76 ERA in limited action, with Guardians hitters posting a .234 average and .642 OPS against him in available data).

Griffin holds a clearer edge in overall season performance and control.

Venue and Weather

Oriole Park at Camden Yards (Baltimore, MD). Forecast for game time: Mostly sunny/partly cloudy, high near 86–89°F dropping into the upper 70s by evening. South/southwest winds around 10–14 mph (gusts possible up to 20–25 mph). Rain chance near 0–2%; no delays expected. Conditions favor playability with modest wind impact (possible slight boost for left-handed power or flies to certain fields).

Injury Reports

Guardians:

Chase DeLauter (RF): Day-to-day (wrist/hamstring notes; out of recent lineups but improving and probable for availability).

Rhys Hoskins (1B): 10-day IL (back/lower back inflammation; hopeful for later September return).

Colin Holderman (RP): 15-day IL (wrist).

Shawn Armstrong (RP): 60-day IL (leg/calf).

Orioles:

Gunnar Henderson (SS): Day-to-day (foot; left early recently but probable).

Blaze Alexander (3B/INF): Day-to-day (back spasms; probable).

Luis Robert Jr. (CF): 10-day IL (hamstring).

Christian Franklin (OF): 10-day IL (hand).

Tyler O’Neill (OF): 10-day IL (shoulder).

Longer-term: Ryan Mountcastle (1B, 60-day IL foot/oblique), Jordan Westburg (INF, 60-day IL UCL), Felix Bautista (RP, 60-day IL shoulder), Ryan Helsley (RP, 60-day IL elbow; progressing with live BP), Zach Eflin, Keegan Akin, and others on 60-day IL.

Recent Guardians order (vs. RHP): Steven Kwan (LF), Travis Bazzana (2B), José Ramírez (3B), Jo Adell (DH), Nathaniel Lowe (1B), Angel Martínez (RF), Patrick Bailey (C), Petey Halpin (CF), Brayan Rocchio (SS).

Recent Orioles order: Jackson Holliday (2B), Pete Alonso (1B), Gunnar Henderson (SS), Coby Mayo (DH), Samuel Basallo (C), Dylan Beavers (LF), Blaze Alexander (3B), Colton Cowser (CF), Leody Taveras (RF). Expect similar constructions with possible DeLauter/Henderson adjustments.

Key active contributors: For Cleveland — Kwan (hot recently, .280+ range in last 10), Ramírez, Bazzana (recent power), Lowe, Rocchio. For Baltimore — Alonso (power leader), Mayo (21 HR, multi-hit recent), Henderson (when available), Holliday, Cowser.

Key Player vs. Player Matchups

Griffin (LHP) vs. Orioles right-handed power (Alonso, Mayo) and lefty bats (Holliday, Henderson). Limited prior data favors Griffin (very low averages for Alonso/Henderson in small samples).

Orioles have been middling vs. LHP overall this season. Baz (RHP) vs. Guardians lefties (Kwan, Bazzana, Lowe, DeLauter if active) and switch-hitters (Ramírez, Rocchio).

Guardians hitters have posted roughly .234 AVG/.642 OPS in available career samples vs. Baz; Ramírez and Rocchio have shown some success. Guardians rank lower in overall offense (team .237 AVG, modest power) but can manufacture runs.

Bullpens: Cleveland’s relief has been reliable lately (strong late-inning metrics); Baltimore’s is depleted by injuries to high-leverage arms.

Recent Team Forms

Guardians (last 10: 6-4): .252 team AVG, 4.05 ERA, even run differential. Won 9-5 Tuesday to even the series after a Monday loss. Stronger road record (38-33). Sitting second in AL Central (2 GB of White Sox) and holding a slim lead for the final AL wild-card spot (ahead of Toronto and others). Recent wins show improved confidence.

espn.co.uk

Orioles (last 10: 3-7): .201 team AVG, 3.59 ERA, outscored by 10. Lost seven of eight entering the series; snapped a skid with Monday’s 6-4 win but dropped Tuesday. Home record 35-39. Fifth in AL East; playoff odds have faded sharply (under 5% in recent estimates) despite stronger overall power (175 HR). Offense has been inconsistent.

espn.co.uk

Series History

Current three-game set is tied 1-1 (Orioles won Monday 6-4; Guardians won Tuesday 9-5). Season series: Guardians lead 4-2 (seven meetings total including this one). Earlier 2026 meetings favored Cleveland in most results. Historical recent matchups have been competitive.

Betting Trends

Orioles have gone Under in a high percentage of recent home games (e.g., 17 of last 25 home).

Baz Under-friendly in several recent home starts vs. winning teams.

Guardians strong as road favorites in recent samples and vs. RHP.

Series games have gone Over early; both offenses can spike but starters favor lower scoring.

Guardians better overall vs. LHP contexts in some splits; Orioles middling vs. lefties.

GAME ODDS

Cleveland Guardians      – 115

Baltimore Orioles            9

Odds Courtesy of Sports Odds Direct as of Tuesday, September 8, 2026

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