Venue: American Family Field, Milwaukee, Wisconsin.
First pitch: 7:40 p.m. ET.
TV/Streaming: Brewers.TV and Marquee Sports Network (MARQ); streaming options include Fubo.
Starting Pitchers
Cubs: LHP David Peterson (7-8, 5.39 ERA, 1.56 WHIP, 113 K in 127.0 IP). Peterson has battled inconsistency with elevated walk and hit rates. He provides a left-handed look but has been vulnerable to hard contact at times this season.
Brewers: RHP Jacob Misiorowski (14-5, 1.97 ERA, 0.79 WHIP, 227 K in 155.0 IP). Misiorowski has been one of the NL’s elite starters, posting dominant strikeout numbers, excellent command, and one of the lowest ERAs in baseball. He is a strong Cy Young candidate and holds a massive edge in this matchup.
Misiorowski’s elite peripherals and win-loss record give Milwaukee a clear pitching advantage.
Weather Forecast
Partly sunny to mostly cloudy with a chance of showers. Highs around 78–80°F, game-time temperatures in the mid-to-upper 70s. South winds 5–15 mph. 40–50% chance of light showers earlier, with better chances of showers/thunderstorms developing later in the evening or overnight. Generally playable conditions with only modest rain risk during the game.
Injury Reports
Cubs:
Ian Happ (LF): Day-to-day (knee; probable).
Dansby Swanson (SS): 10-day IL (side/oblique).
Edward Cabrera (SP): 15-day IL (blister/finger).
Gavin Hollowell (RP): 15-day IL (shoulder).
Longer-term: Justin Steele, Shelby Miller, Hunter Harvey, Cade Horton, and others on 60-day IL (mostly elbow/arm issues).
Grant Anderson (RP): 15-day IL (biceps).
Bryse Wilson (SP/RP): 15-day IL (back).
Longer-term: Brandon Woodruff, Rob Zastryzny, Brian Fitzpatrick, Angel Zerpa, Quinn Priester (shoulder/elbow/wrist issues on 60-day IL).
Both clubs have bullpen and depth concerns, though Milwaukee’s rotation strength (led by Misiorowski) mitigates some of the impact. Cubs miss key middle-infield stability with Swanson out.
Current Rosters / Key Players
Cubs key contributors: Pete Crow-Armstrong (elite power/speed, ~41 HR, high average), Alex Bregman (hot recently with multi-HR stretches), Seiya Suzuki, Nico Hoerner, and supporting pieces. Team batting ~.251 with strong power output (203 HR).
Brewers key contributors: Jackson Chourio (consistent production and recent hot stretches), Brice Turang, William Contreras, Christian Yelich, and a balanced lineup leading the NL in team batting average (.256). Strong home performance (48-25).
Key Player vs. Player Matchups
Peterson vs. Brewers hitters: Faces a high-average, athletic Milwaukee lineup led by Chourio’s bat-to-ball skills and Turang’s production. Peterson’s left-handed arsenal can induce weak contact but elevated WHIP raises risk against patient hitters.
Misiorowski vs. Cubs hitters: Elite stuff and strikeout rate challenge Chicago’s power core (Crow-Armstrong, Bregman). Misiorowski has dominated most of the season and limited hard contact effectively.
This is Game 2 of the three-game series (Brewers took the opener 4-3 on Monday with a late rally). Season series favors Milwaukee (7-4 entering the game).
Recent Team Forms
Cubs: 5-5 last 10. Competitive but falling further behind in the division (eight games back after Monday’s loss). Solid road mark (40-33) and strong when limiting home runs.
Brewers: 5-5 last 10 but overall excellent (89-56, first in NL Central). Dominant at home and in possession of the best record in the National League. They hold a 1-0 series lead.
Series History
Part of a heated NL Central rivalry. The Brewers lead the 2026 season series and took Game 1 of this set. These clubs have met multiple times recently; Milwaukee has generally held the upper hand in 2026 head-to-head play. Both remain in strong playoff positions, with Milwaukee locking in a division lead and Chicago fighting for a wild-card spot.
Betting Trends
Heavy home favorites with the far superior starter. Public heavily supports Milwaukee given Misiorowski’s dominance and the Brewers’ overall record/home strength. Totals are relatively low, reflecting the pitching matchup.
Game Odds
Chicago Cubs 7.5
Milwaukee Brewers – 206
Odds Courtesy of Sports Odds Direct as of Monday, September 7, 2026
