Location: Wrigley Field — Chicago, Illinois
Start Time: 2:20 PM EDT
Weather: Forecast shows cool Chicago conditions (approx. 9°C / 48°F) at gametime.
Injury Report
Chicago Cubs
Multiple pitchers remain sidelined, including:
Ethan Roberts (finger), Daniel Palencia (oblique), Riley Martin (elbow), Hunter Harvey (tricep), Porter Hodge (elbow), Caleb Thielbar (hamstring), Jordan Wicks (forearm), Shelby Miller (elbow), Justin Steele (elbow), Christopher Austin (knee), Cade Horton (forearm).
Nico Hoerner: day‑to‑day (neck).
Arizona Diamondbacks
Key injuries include:
Carlos Santana (groin), Jordan Lawlar (wrist), Tyler Locklear (elbow), A.J. Puk (elbow), Blake Walston (elbow), Andrew Saalfrank (shoulder), Cristian Mena (shoulder), Corbin Burnes (elbow), Pavin Smith (elbow), Justin Martinez (elbow).
Pitching Matchup
Arizona — Ryne Nelson (1–2, 7.71 ERA, 1.52 WHIP, 24 K)
Chicago — Shota Imanaga (2–2, 3.15 ERA, 0.87 WHIP, 38 K)
Edge: Cubs. Imanaga has been excellent at home and owns elite command metrics, while Nelson has struggled badly with run prevention.
Team Records & Recent Form
Arizona Diamondbacks (16–15)
Road record: 7–9
Last 10: 3–7, with a 7.86 ERA and outscored by 28 runs.
Season run differential: –? (from 5.52 RA vs. 4.71 RF).
Chicago Cubs (20–12)
Home record: 12–5
Last 10: 7–3, hitting .279, outscoring opponents, ERA 5.32.
Season run differential: +? (5.47 RF vs. 4.34 RA).
Form Advantage: Cubs (significant).
Key Player Matchups
Cubs Offense
Nico Hoerner: .297 AVG, 9 doubles, 4 HR.
Seiya Suzuki: 14-for-36, 5 HR, 7 RBI in last 10.
Diamondbacks Offense
Ildemaro Vargas: .404 AVG, 6 doubles, 2 triples, 6 HR, 21 RBI.
Nolan Arenado: 13-for-32, 2 HR, 6 RBI last 10.
Series History
Cubs lead season series 1–0 after a 6–5 win on May 1.
Last 10 H2H: Cubs lead 6–4.
Betting Trends
Cubs
20–12 overall, 12–5 at home.
7–3 last 10; 9–1 to the Over in that span.
Diamondbacks
3–7 last 10; pitching staff allowing 7.86 ERA recently.
7–3 to the Over in last 10.
GAME ODDS
Arizona Diamondbacks 7
Chicago Cubs – 171
Odds Courtesy of Sports Odds Direct as of Friday, May 1, 2026
