MLB Game Preview: Chicago White Sox (9-15) vs. Arizona Diamondbacks (14-10)

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10
Arizona Diamondbacks logo

Venue: Chase Field — Phoenix, Arizona

Start Time: 3:40 PM EDT (12:40 PM local)

Weather Outlook

Temperature: 68–88°F range around Phoenix on gameday (Fox Sports listing)

Conditions: Indoors when roof is closed; Chase Field frequently closes roof for heat. (Inference based on venue norms.)

Injury Report

Arizona Diamondbacks

Multiple key players remain sidelined:

Tyler Locklear — 10‑Day IL (elbow)

A.J. Puk — 60‑Day IL (elbow)

Blake Walston — 60‑Day IL (elbow)

Carlos Santana — 10‑Day IL (groin)

Jordan Lawlar — 60‑Day IL (wrist)

Andrew Saalfrank — 60‑Day IL (shoulder)

Gabriel Moreno — 10‑Day IL (back)

Cristian Mena — 60‑Day IL (shoulder)

Corbin Burnes — 60‑Day IL (elbow)

Pavin Smith — 60‑Day IL (elbow)

Justin Martinez — 60‑Day IL (elbow)

Chicago White Sox

Chris Murphy — 15‑Day IL (elbow)

Ky Bush — 60‑Day IL (elbow)

Kyle Teel — 10‑Day IL (hamstring)

Drew Thorpe — 15‑Day IL (elbow)

Brooks Baldwin — 60‑Day IL (elbow)

Jonathan Cannon — 15‑Day IL (hip)

Mike Vasil — 60‑Day IL (elbow)

Prelander Berroa — 60‑Day IL (elbow)

Austin Hays — 10‑Day IL (hamstring)

Probable Pitching Matchup

CWS — Davis Martin (RHP)

Record: 3–1

ERA: 2.16

WHIP: 1.00

Strikeouts: 19

ARI — Mike Soroka (RHP)

Record: 4–0

ERA: 2.78

WHIP: 1.06

Strikeouts: 28

Team Records & Recent Form

Chicago White Sox (9–15)

Road Record: 6–9

Last 5: L, W, W, L, W (from sports card)

Last 10: 4–6, .255 AVG, 5.55 ERA, even run differential

Arizona Diamondbacks (14–10)

Home Record: 8–4

Last 5: W, L, L, W, W (from sports card)

Last 10: 6–4, .287 AVG, 5.56 ERA, +1 run differential

Series History

This is the third meeting of the season.

Arizona enters after Nolan Arenado’s four‑hit game on Wednesday.

Key Player Matchups

Arizona

Ildemaro Vargas: .364 AVG, 5 HR, 16 RBI

Geraldo Perdomo: 13‑for‑36 with 3 triples in last 10

Chicago

Munetaka Murakami: 10 HR (2nd on team), 16 RBI

Colson Montgomery: 9‑for‑37, 5 HR, 11 RBI in last 10

Betting Trends

Arizona owns the 4th‑best slugging percentage in MLB (.422).

White Sox are 7–4 when scoring 5+ runs, but average only 3.7 runs/game.

Soroka is undefeated (4–0) and Arizona is 8–4 at home.

Game Odds

Chicago White Sox                          9

Arizona Diamondbacks                 – 156

Odds Courtesy of Sports Odds Direct as of Wednesday, April 22, 2026